1515606-23-1

Basic information

• Product Name: N-Cbz-D-Ser[N-Me-Val]-(S)-β-L-triisopropylsilyloxy-Pip-Gly-Sar allyl ester
• Synonyms: N-Cbz-D-Ser[N-Me-Val]-(S)-β-L-triisopropylsilyloxy-Pip-Gly-Sar allyl ester
• CAS NO: 1515606-23-1
• Molecular Weight: 804.069
• Mol File: 1515606-23-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-Cbz-D-Ser[N-Me-Val]-(S)-β-L-triisopropylsilyloxy-Pip-Gly-Sar allyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-Cbz-D-Ser[N-Me-Val]-(S)-β-L-triisopropylsilyloxy-Pip-Gly-Sar allyl ester(1515606-23-1)
• EPA Substance Registry System: N-Cbz-D-Ser[N-Me-Val]-(S)-β-L-triisopropylsilyloxy-Pip-Gly-Sar allyl ester(1515606-23-1)

Safety Data

• Hazardous Substances Data: 1515606-23-1(Hazardous Substances Data)

Upstream product

• 1515605-77-2 (S)-5-azido-2-triisopropylsilyloxy-1-pentanol 
• 1515605-42-1 N-Cbz-D-Ser[N-Me-Boc-Val]-(S)-β-L-triisopropylsilyloxy-Pip-Gly-Sar allyl ester 
• 133498-97-2 t-BuOCO-Gly-Sar-OH 
• 29816-01-1 Glycylsarcosine 
• 1515605-55-6 N-Boc-Gly-Sar allyl ester 
• 1515606-17-3 C₈H₁₄N₂O₃*ClH 
• 1515605-59-0 N-formyl-Gly-Sar allyl ester 
• 78700-33-1 Z-D-Ser-OTce 
• 45170-31-8 Boc-N-Me-Val-OH 
• 170277-82-4 (2S)-1-triphenylmethoxy-4-pentene-2-ol 
• 80522-42-5 triisopropylsilyl trifluoromethanesulfonate 
• 1515605-46-5 2-propenyl 2-(2-isocyano-N-methylacetamido)acetate 
• 1515606-36-6 C₄₀H₅₂O₅SSi 
• 1515605-49-8 C₁₄H₂₉NOSi 

Downstream Products

• 1515605-94-3 N-Cbz-D-Ser{N-Cbz-D-Ser[(N-Boc-N-Me-L-Val)-(S)-β-L-triisopropylsilyloxy-Pip-Gly-Sar-N-Me-L-Val]}-(S)-β-L-triisopropylsilyloxy-Pip-Gly-Sar allyl ester 

Relevant articles and documents

Total synthesis of sandramycin and its analogues via a multicomponent assemblage

The total synthesis of sandramycin has been accomplished by using a Staudinger/aza-Wittig/diastereoselective Ugi three-component reaction sequence as a key step to obtain a linear pentadepsipeptide. Subsequent [5 + 5] coupling of the penptapeptide, macrolactamization, and introduction of the quinaldin chromophores afforded sandramycin. Dihydroxy and diacetoxy analogues were also prepared, and the cytotoxic activity of these analogues against a range of human cancer cell lines was evaluated.