133498-97-2

Basic information

• Product Name: Glycine, N-[(1,1-dimethylethoxy)carbonyl]glycyl-N-methyl-
• CAS NO: 133498-97-2
• Molecular Formula: C10H18N2O5
• Molecular Weight: 246.263
• Mol File: 133498-97-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Glycine, N-[(1,1-dimethylethoxy)carbonyl]glycyl-N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine, N-[(1,1-dimethylethoxy)carbonyl]glycyl-N-methyl-(133498-97-2)
• EPA Substance Registry System: Glycine, N-[(1,1-dimethylethoxy)carbonyl]glycyl-N-methyl-(133498-97-2)

Safety Data

• Hazardous Substances Data: 133498-97-2(Hazardous Substances Data)

Upstream product

• 29816-01-1 Glycylsarcosine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 4530-20-5 BOC-glycine 
• 174311-10-5 methyl N'-(tert-butoxycarbonyl)glycylsarcosinate 
• 73243-15-9 t-BuOCO-Gly-Sar-OCH₂Ph₂ 

Downstream Products

• 133525-56-1 Boc-Gly-sarcosyl-ψ(CONCH3)Leu-OBn 
• 1515605-42-1 N-Cbz-D-Ser[N-Me-Boc-Val]-(S)-β-L-triisopropylsilyloxy-Pip-Gly-Sar allyl ester 
• 1515606-22-0 C₄₅H₇₃N₅O₁₂Si 
• 1515605-80-7 N-Cbz-D-Ser[N-Me-Boc-Val]-(S)-β-L-hydroxy-Pip-Gly-Sar allyl ester 
• 1515605-84-1 N-Cbz-D-Ser[N-Me-Boc-Val]-L-Pip-Gly-Sar allyl ester 
• 1515605-90-9 N-Cbz-D-Ser[N-Me-Boc-Val]-L-Pip-Gly-Sar-OH 
• 100940-65-6 sandramycin 
• 1515606-23-1 N-Cbz-D-Ser[N-Me-Val]-(S)-β-L-triisopropylsilyloxy-Pip-Gly-Sar allyl ester 
• 1515606-24-2 N-Cbz-D-Ser[N-Boc-N-Me-L-Val]-(S)-β-L-triisopropylsilyloxy-Pip-Gly-Sar-OH 
• 1515605-81-8 C₄₃H₅₇N₅O₁₃S 
• 1515605-87-4 C₃₁H₄₅N₅O₉*ClH 
• 1574776-16-1 C₆₁H₈₈N₁₀O₁₉ 
• 1515606-29-7 C₅₆H₈₀N₁₀O₁₇ 
• 174311-16-1 N¹-SES-N⁶-<<3-(benzyloxy)quinolyl>-2-carbonyl>-(D-Ser-Pip-Gly-Sar-NMe-Val)2(serine hydroxyl) dilactone 

Relevant articles and documents

Total synthesis of sandramycin and its analogues via a multicomponent assemblage

The total synthesis of sandramycin has been accomplished by using a Staudinger/aza-Wittig/diastereoselective Ugi three-component reaction sequence as a key step to obtain a linear pentadepsipeptide. Subsequent [5 + 5] coupling of the penptapeptide, macrolactamization, and introduction of the quinaldin chromophores afforded sandramycin. Dihydroxy and diacetoxy analogues were also prepared, and the cytotoxic activity of these analogues against a range of human cancer cell lines was evaluated.

(-)-Sandramycin: Total synthesis and characterization of DNA binding properties

Full details of the total synthesis of the potent antitumor antibiotic (-)-sandramycin (1), a cyclic decadepsipeptide possessing a 2-fold axis of symmetry, is described and constitutes the first total synthesis of a member of the growing class of naturall

C-alkylation of peptides through polythiated and LiCl-solvated derivatives containing sarcosine Li-enolate units

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