15160-31-3

Basic information

• Product Name: BOC-TRP-ONP
• Synonyms: N-ALPHA-BOC-L-TRYPTOPHAN 4-NITROPHENYL ESTER;BOC-L-TRYPTOPHAN P-NITROPHENYL ESTER;BOC-L-TRYPTOPHAN 4-NITROPHENYL ESTER;BOC-TRP-ONP;BOC-TRYPTOPHAN-ONP;4-nitrophenyl N-[(tert-butoxy)carbonyl]-L-tryptophanate;N-tert-Butoxycarbonyl-L-tryptophan4-nitrophenylester;Boc-L-Trp-ONp
• CAS NO: 15160-31-3
• Molecular Formula: C₂₂H₂₃N₃O₆
• Molecular Weight: 425.43
• EINECS: 239-214-6
• Product Categories: Amino Acids
• Mol File: 15160-31-3.mol

Chemical Properties

• Boiling Point: 651.3°Cat760mmHg
• Flash Point: 347.7°C
• Appearance: /
• Density: 1.313g/cm³
• Vapor Pressure: 7.58E-17mmHg at 25°C
• Refractive Index: 1.621
• Storage Temp.: -15°C
• PKA: 10.82±0.46(Predicted)
• CAS DataBase Reference: BOC-TRP-ONP(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-TRP-ONP(15160-31-3)
• EPA Substance Registry System: BOC-TRP-ONP(15160-31-3)

Safety Data

• Hazardous Substances Data: 15160-31-3(Hazardous Substances Data)

Usage

Chemical Properties

Yellow powder

InChI:InChI=1/C22H23N3O6/c1-22(2,3)31-21(27)24-19(12-14-13-23-18-7-5-4-6-17(14)18)20(26)30-16-10-8-15(9-11-16)25(28)29/h4-11,13,19,23H,12H2,1-3H3,(H,24,27)

Upstream product

• 100-02-7 4-nitro-phenol 
• 13139-14-5 Boc-Trp-OH 

Downstream Products

• 94776-64-4 Boc-Trp-Glu(OBzl)-Val-OBzl 
• 94991-11-4 tert-Butyloxycarbonyl-L-tryptophyl-L-seryl-L-tyrosylglycine Methyl Ester 
• 94236-70-1 Boc-L-Trp-L-Leu-L-Asp(Bzl)-N(CH₃)2 
• 94236-59-6 Boc-L-Trp-L-Nle-L-Asp(Bzl)-NH₂ 
• 92762-81-7 (tert-butyloxycarbonyl)-L-tryptophyl-L-methionyl-β-benzyl-L-aspartic acid amide 
• 94236-61-0 Boc-L-Trp-L-Phe-L-Asp(Bzl)-NH₂ 
• 94236-69-8 Boc-L-Trp-L-Leu-L-Asp(Bzl)-Pip 
• 94236-65-4 Boc-L-Trp-L-Leu-L-Asp(Bzl)2 
• 94236-66-5 Boc-L-Trp-L-Leu-D-Asp(Bzl)-NH₂ 
• 103934-32-3 (tert-butyloxycarbonyl)-L-tryptophyl-L-leucyl-β-benzyl-L-aspartic acid phenethyl ester 
• 103934-41-4 Boc-Trp-Leu-Asp(Bzl) p-fluorophenethyl ester 
• 139369-71-4 (S)-2-Amino-3-(1H-indol-3-yl)-propionic acid 4-nitro-phenyl ester 
• 178430-86-9 (S)-2-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-2-phenyl-acetylamino}-succinic acid 4-benzyl ester 
• 127292-64-2 (S)-2-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-3-methyl-butyric acid; compound with dicyclohexyl-amine 

Relevant articles and documents

SULFOXONIUM YLIDE DERIVATIVES AS PROBES FOR CYSTEINE PROTEASE

The present invention relates to compounds of formula I bearing a sulfoxonium ylide moiety as warhead, or salts thereof. Such compounds can be used as activity-based probes for cysteine proteases such as cathepsin X, in methods of detecting cysteine protease activity and in related diagnostic or therapeutic methods.

Synthesis and antimicrobial activity of 7-Amino cephalosporanic acid derivatives of amino acids and peptides

A novel series of 7-amino cephalosporanic acid derivatives of amino acid and peptides were synthesized by solution phase technique. The synthesized compounds were tested for their biological activities against bacterial and fungal organisms. All the compounds showed potent antifungal activity and most of the compounds have shown moderate antibacterial activities. The structures of the newly synthesized compounds were confirmed by IR, 1H NMR and mass spectral analysis.