151620-16-5Relevant articles and documents
Synthesis and SAR of new 5-phenyl-3-ureido-1,5-benzodiazephines as cholecystokinin-B receptor antagonists
Ursini,Capelli,Carr,Cassarà,Corsi,Curcuruto,Curotto,Dal Cin,Davalli,Donati,Feriani,Finch,Finizia,Gaviraghi,Marien,Pentassuglia,Polinelli,Ratti,Reggiani,Tarzia,Tedesco,Tranquillini,Trist,Van Amsterdam
, p. 3596 - 3613 (2007/10/03)
A series of 5-phenyl-3-ureidobenzodiazepine-2,4-diones was synthesized and evaluated as cholecystokinin-B (CCK-B) receptor antagonists. Structure-activity relationship (SAR) studies revealed the importance of the N-1 substituent for potent and selective C