151630-98-7

Usage

Uses

Used in Pharmaceutical Industry:
(2S,3S)-2,3-Diaminobutane-1,4-diol is used as a chiral building block for the synthesis of chiral drugs and fine chemicals. Its chiral nature allows for the development of enantiopure compounds, which are essential for the pharmaceutical industry and drug development.
Used in Organic Synthesis:
(2S,3S)-2,3-Diaminobutane-1,4-diol is used as a starting material for the creation of various chiral molecules in organic synthesis, making it a valuable component in the synthesis of complex organic compounds.
Used in Neurodegenerative Disease Treatment:
(2S,3S)-2,3-Diaminobutane-1,4-diol has been studied for its potential application in the treatment of neurodegenerative diseases, offering a promising avenue for therapeutic intervention in conditions such as Alzheimer's and Parkinson's diseases.
Used as a Catalyst in Chemical Reactions:
(2S,3S)-2,3-Diaminobutane-1,4-diol has been explored as a catalyst in certain chemical reactions, demonstrating its versatility and utility in various chemical processes.

Upstream product

• 133268-20-9 D-2,3-diazido-1,4-dibenzoylbutane 
• 131063-52-0 (2R,3R)-2,3-diazidobutane-1,4-diol 

Downstream Products

• 1445949-44-9 C₂₀H₂₄N₂O₆ 

Relevant academic research and scientific papers

Multiple-Hydrogen-Bond Approach to Uncommon Pd(III) Oxidation State: A Pd-Br Chain with High Conductivity and Thermal Stability

A Br-bridged Pd chain complex with the Pd ion in an uncommon +3 oxidation state, [Pd(dabdOH)2Br]Br2 (3), was prepared using a new method involving multiple hydrogen bonds. The PdBr chain complex exhibited superior electrical conductivity and thermal stability. An in-plane ligand with an additional hydrogen donor group (hydroxy group), (2S,3S)-2,3-diaminobutane-1,4-diol (dabdOH), was used to create a multiple-hydrogen-bond network, which effectively shrinks the Pd-Br-Pd distance, stabilizing the Pd(III) state up to its decomposition temperature (443 K). 3 shows semiconducting behavior with quite high electrical conductivity (3-38 S cm-1 at room temperature), which is 106 times larger than the previous record for analogous PdBr chains. Indeed, 3 is the most conductive MX-type chain complex reported so far. The precise positional control of ions via a multiple-hydrogen-bond network is a useful method for controlling the electronic states, thermal stability and conductivity of linear coordination polymers.

New supramolecular host systems, 11. The stereoisomeric diaminobutanediol and dioxadiazadecalin systems: Synthesis, structure, stereoelectronics, and conformation - Theory vs. experiment

We present new approaches to the (C2) chiral and meso 1,4-diamino-2,3- butanediol (1) and 2,3-diamino-1,4-butanediol (2) and derivatives. Reactions of these compounds with aldehydes to form the novel 1,5-dioxa-3,7- diazadecalin (DODAD) and 1,5-diaza-3,7-dioxadecalin (DADOD) classes of compounds (7, 9, 11-15) are also reported. These reactions are diastereospecific, i e, erythro (meso) or threo starting compounds lead to trans or cis products, respectively. The structural, conformational, and stereoelectronic aspects of these systems were probed experimentally and computationally and provided excellent insight into their properties and behaviour. Good agreement was observed between X-ray, NMR, and calculated results of the N,N'-dibenzyl derivatives of trans-DODAD (14) and trans-DADOD (15).

Efficient synthesis of (2R,3R)- and (2S,3S)-2,3-diaminobutane-1,4-diol and their dibenzyl ethers

(2R,3R)-2,3-Diaminobutane-1,4-diol 6 and its dibenzyl ether 7 were efficiently synthesized starting from L-tartaric acid 1a. The crucial step, debenzylation of intermediate dibenzyloxydiazide 4, was accomplished in good yield by boron trichloride-dimethyl sulfide complex. The enantiomeric series was similarly obtained starting from D-tartaric acid.