15166-39-9

Upstream product

• 15062-88-1 2-hydrazino-1,3-benzoxazole 
• 100-52-7 benzaldehyde 
• 116577-78-7 3-phenylbenzo[4,5]oxazolo[2,3-c][1,2,4]triazole 

Downstream Products

• 34654-38-1 1-benzooxazol-2-yl-5-naphthalen-1-yl-3-phenyl-formazan 
• 16586-64-4 1-benzooxazol-2-yl-3-phenyl-5-p-tolyl-formazan 
• 15166-43-5 2-(N'-benzyl-hydrazino)-benzooxazole 
• 116577-78-7 3-phenylbenzo[4,5]oxazolo[2,3-c][1,2,4]triazole 

Relevant academic research and scientific papers

Condensation and Cyclization of 2-Hydrazinobenzimidazole, -benzoxazole, and -benzothiazole

2-Hydrazinobenzoxazole (1), -benzimidazole (2), and -benzothiazole (3) were condensed with ethyl chloroformate and/or diethyl oxalate to produce 1,2,4-triazolo- and 1,2,4-triazino-fused ketones of the title azoles respectively.Condensation of 1 and 2 with aromatic aldehydes and/or acetic anhydride produced, 3-aryl- and 3-methyl-substituted 1,2,4-triazolo-fused azoles respectively.The hydrazines 1 and 2 cyclized with acetylacetone to produce the corresponding 2-(1-pyrazolyl) derivatives. 2-Acetylthiazolobenzimidazole reacted with hydroxylamine and/or alkylamines, to produce the corresponding condensation products.Also, it condensed with aromatic aldehydes to give the chalcones.When reacted with benzenediazonium salt, it gave the corresponding 2-arylazo-substituted compounds.

Study of oxidative cyclization using PhI(OAc)2 in the formation of benzo[4,5]thiazolo[2,3- C ][1,2,4]triazoles and related heterocycles - Scope and limitations

A one-pot, two-step reaction for the synthesis of benzo[4,5]thiazolo[2,3-c] [1,2,4]triazoles and related heterocycles under mild conditions was herein developed. The key step of this transformation is an oxidative cyclization employing PhI(OAc)2/sub