151675-59-1 Usage
Uses
Used in Pharmaceutical Industry:
5-(Dimethylamino)-5-oxopentanoic acid is used as a reagent for the synthesis of leukotriene B4 analogs, which are important in the development of new drugs targeting leukotriene receptors. These analogs exhibit improved receptor binding activity, making them valuable for the treatment of various inflammatory and allergic conditions.
In the synthesis process, 5-(Dimethylamino)-5-oxopentanoic acid serves as a key building block, providing the necessary structural elements for the formation of leukotriene B4 analogs with enhanced biological activity. This application highlights the compound's utility in the development of novel therapeutic agents with potential benefits for patients suffering from a range of diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 151675-59-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,6,7 and 5 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 151675-59:
(8*1)+(7*5)+(6*1)+(5*6)+(4*7)+(3*5)+(2*5)+(1*9)=141
141 % 10 = 1
So 151675-59-1 is a valid CAS Registry Number.
151675-59-1Relevant academic research and scientific papers
Foubelo, Francisco,Lloret, Francisco,Yus, Miguel
, p. 8465 - 8470 (1993)
The reaction of iodoacetic acid 1 with tributyltin chloride and sodium borohydride in the presence of different electrophilic olefins 2 (methyl, allyl or tert-butyl acrylates, N,N-dimethyl or N,N-di-iso-propyl acrylamides, acrylonitrile, methyl methacrylate, methacrylonitrile and 1,1-dichloroethylene) and AIBN as an initiator yields, after treatment with aqueous sodium fluoride, the corresponding products 3 through a radical Michael-type process.