
Tetrahedron p. 8465 - 8470 (1993)
Update date:2022-09-26
Topics:
Foubelo, Francisco
Lloret, Francisco
Yus, Miguel
The reaction of iodoacetic acid 1 with tributyltin chloride and sodium borohydride in the presence of different electrophilic olefins 2 (methyl, allyl or tert-butyl acrylates, N,N-dimethyl or N,N-di-iso-propyl acrylamides, acrylonitrile, methyl methacrylate, methacrylonitrile and 1,1-dichloroethylene) and AIBN as an initiator yields, after treatment with aqueous sodium fluoride, the corresponding products 3 through a radical Michael-type process.
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(2004)Doi:10.1111/cbdd.12380
(2015)Doi:10.1002/hc.21246
(2015)Doi:10.1081/SCC-200054195
(2005)