15173-54-3 Usage
Uses
Used in Pharmaceutical Industry:
3-BETA-HYDROXY-5-ALPHA-ANDROSTANE-17-BETA-CARBOXYLIC ACID is used as a therapeutic agent for the treatment of male hypogonadism, a condition characterized by insufficient androgen production in men, leading to various symptoms such as low libido, fatigue, and reduced muscle mass. It helps in restoring normal hormone levels and alleviating the symptoms associated with this condition.
3-BETA-HYDROXY-5-ALPHA-ANDROSTANE-17-BETA-CARBOXYLIC ACID is also used as a treatment for androgen insensitivity syndrome, a genetic disorder in which individuals with a male karyotype (46, XY) have a partial or complete inability to respond to androgens, resulting in a range of phenotypes from male infertility to a completely female appearance. 3-BETA-HYDROXY-5-ALPHA-ANDROSTANE-17-BETA-CARBOXYLIC ACID can help in managing the symptoms and improving the quality of life for affected individuals.
Furthermore, 3-BETA-HYDROXY-5-ALPHA-ANDROSTANE-17-BETA-CARBOXYLIC ACID is used in the treatment of certain types of breast cancer, particularly those that are hormone receptor-positive. It may have potential anti-tumor effects by modulating the hormonal environment and interfering with the growth and progression of cancer cells.
Check Digit Verification of cas no
The CAS Registry Mumber 15173-54-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,1,7 and 3 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 15173-54:
(7*1)+(6*5)+(5*1)+(4*7)+(3*3)+(2*5)+(1*4)=93
93 % 10 = 3
So 15173-54-3 is a valid CAS Registry Number.
InChI:InChI=1/C20H32O3/c1-19-9-7-13(21)11-12(19)3-4-14-15-5-6-17(18(22)23)20(15,2)10-8-16(14)19/h12-17,21H,3-11H2,1-2H3,(H,22,23)
15173-54-3Relevant academic research and scientific papers
COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS
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, (2021/01/23)
Provided herein is a compound of Formula I, II, IlIa, IlIb, V, VIa, VIb, VII, VIII, IX, or XI: or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of Formula I, II, IlIa, IlIb, V, VIa, VIb, VII, VIII, IX, or X, and methods of using the compounds, e.g., in the treatment of CNS-related disorders.
SYNTHESES OF 17β-(2-MALEIMIDO)ANDROSTANES
Drasar, Pavel,Havel, Miroslav
, p. 1976 - 1982 (2007/10/02)
Starting from pregnane derivatives, 17β-(2-maleimido)androstanes of 5α- and Δ5-series, with and without a 3β-acetoxy group, were prepared via methyl 3-androstanyl-3-cyano acrylates.The maleimidoandrostanes were synthesized as models for cardiotonic steroids.
Absolute configuration at C(20) of the derivatives of 21-nor-5α-cholane-20,24-diol
Pouzar, Vladimir,Havel, Miroslav
, p. 2443 - 2451 (2007/10/02)
Derivatives of 21-nor-5α-cholane-20,24-diol XI and XIX were prepared by stepwise construction of the side-chain in the position 17β.Their absolute configuration at C(20) was determined on the basis of chemical correlation with the derivatives of 21-nor-5α-cholan-20-ol, XVI and XXIV.The absolute configuration of alcohols XVI and XXIV was determined from the ratio of the yields in which they are formed during the reduction of ketone X and using the benzoate rule.To compounds XI-XVIII the configuration 20R and to compounds XIX-XXVI the configuration 20S has been assigned.
