15182-67-9

Basic information

• Product Name: 1,2-dihydro-1-(o-methoxyphenyl)-5H-tetrazole-5-thione
• Synonyms: 1,2-dihydro-1-(o-methoxyphenyl)-5H-tetrazole-5-thione;1,2-Dihydro-1-(2-methoxyphenyl)-5H-tetrazole-5-thione;Einecs 239-231-9
• CAS NO: 15182-67-9
• Molecular Formula: C₈H₈N₄OS
• Molecular Weight: 208.24032
• EINECS: 239-231-9
• Mol File: 15182-67-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 165 °C (decomp)
• Boiling Point: 288.9°Cat760mmHg
• Flash Point: 128.5°C
• Appearance: /
• Density: 1.45g/cm³
• Vapor Pressure: 0.00228mmHg at 25°C
• Refractive Index: 1.707
• PKA: -3.20±0.20(Predicted)
• CAS DataBase Reference: 1,2-dihydro-1-(o-methoxyphenyl)-5H-tetrazole-5-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-dihydro-1-(o-methoxyphenyl)-5H-tetrazole-5-thione(15182-67-9)
• EPA Substance Registry System: 1,2-dihydro-1-(o-methoxyphenyl)-5H-tetrazole-5-thione(15182-67-9)

Safety Data

• Hazardous Substances Data: 15182-67-9(Hazardous Substances Data)

Usage

General Description

1,2-dihydro-1-(o-methoxyphenyl)-5H-tetrazole-5-thione is a chemical compound with the molecular formula C9H10N4OS. It is a tetrazole derivative, meaning it contains a five-membered ring with four nitrogen atoms and one sulfur atom. 1,2-dihydro-1-(o-methoxyphenyl)-5H-tetrazole-5-thione has potential pharmaceutical applications due to its interesting biological properties. It has been studied for its potential as an anti-cancer agent, as well as for its antimicrobial and antifungal properties. Additionally, 1,2-dihydro-1-(o-methoxyphenyl)-5H-tetrazole-5-thione has been investigated for its potential use in the development of novel drugs with therapeutic benefits. Its unique structure and biological activities make it an interesting target for further research and potential pharmaceutical development.

InChI:InChI=1/C8H8N4OS/c1-13-7-5-3-2-4-6(7)12-8(14)9-10-11-12/h2-5H,1H3,(H,9,11,14)

Upstream product

• 66654-58-8 5-(o-anisylamino)-1,2,3,4-thiatriazole 
• 854902-49-1 (2-methoxy-phenyl)-dithiocarbamic acid methyl ester 
• 40207-02-1 4-(o-methoxyphenyl)thiosemicarbazide 
• 90-04-0 2-methoxy-phenylamine 
• 53662-51-4 (2-methoxy-phenyl)-dithiocarbamic acid ; compound with triethylamine 
• 3288-04-8 1-isothiocyanato-2-methoxybenzene 

Downstream Products

• 92044-03-6 1-(2-methoxy-phenyl)-4-morpholin-4-ylmethyl-1,4-dihydro-tetrazole-5-thione 
• 1618101-13-5 5-[(3,5-dinitrobenzyl)sulfanyl]-1-(2-methoxyphenyl)-1H-tetrazole 
• 1061907-97-8 C₁₈H₁₈N₄O₄S 

Relevant articles and documents

1-(2-Methoxyphenyl)-1,4-Dihydro-5H-Tetrazole-5-Thione and Its Complex with Cd(II): Molecular and Crystal Structures

Abstract: The molecular and crystal structures of 1-(2-methoxyphenyl)-1,4-dihydro-5H-tetrazole-5-thione (L) and its complex with cadmium(II) (II) are studied by X-ray diffraction analysis (CIF files CCDC nos.?1567109 (L) and 1547252 (II)). Free ligand L is nonplanar thione. The dihedral angle between the tetrazole and benzene cycles is 85.21(7)°. These cycles form centrosymmetric dimers in the crystal by two hydrogen bonds N–H···S. The dimers contain the central planar eight-membered ring {S=C–N–H···S=C–N–H···}. Complex II has a chain structure of the composition [(C8H7N4OS)2Cd]n. The coordination mode of the Сd(II) atom is a distorted tetrahedron consisting of two nitrogen atoms and two sulfur atoms of four ligands L. The 1D chains contain the eight-membered rings {←S=C–N–Cd ← S=C–N–Cd} in the boat conformation. Weak intermolecular hydrogen bonds C–H···N are observed between the adjacent 1D chains along the c axis in the crystal.

Synthesis of some New Antifungal Tetrazolyl Sulphides

-