3288-04-8

Basic information

• Product Name: 2-METHOXYPHENYL ISOTHIOCYANATE
• Synonyms: Benzene, 1-isothiocyanato-2-methoxy-;ISOTHIOCYANIC ACID 2-METHOXYPHENYL ESTER;1-ISOTHIOCYANATO-2-METHOXY-BENZENE;2-METHOXYPHENYL ISOTHIOCYANATE;O-METHOXYPHENYL ISOTHIOCYANATE;o-Anisyl isothiocyanate;2-Methoxy-1-isothiocyanatobenzene;2-Methoxyphenyl isothiocyanate,99%
• CAS NO: 3288-04-8
• Molecular Formula: C₈H₇NOS
• Molecular Weight: 165.21
• EINECS: 626-109-9
• Product Categories: Organic Building Blocks;Sulfur Compounds;Thiocyanates/Isothiocyanates
• Mol File: 3288-04-8.mol
• Article Data: 32

Chemical Properties

• Boiling Point: 264-266 °C
• Flash Point: >110°C
• Appearance: Clear light yellow/Liquid
• Density: 1.19
• Vapor Pressure: 0.0154mmHg at 25°C
• Refractive Index: 1.6433-1.6453
• Water Solubility: Reacts with water.
• Sensitive: Moisture Sensitive
• BRN: 638293
• CAS DataBase Reference: 2-METHOXYPHENYL ISOTHIOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXYPHENYL ISOTHIOCYANATE(3288-04-8)
• EPA Substance Registry System: 2-METHOXYPHENYL ISOTHIOCYANATE(3288-04-8)

Safety Data

• Hazard Codes: T,C
• Statements: 36/37/38-23/24/25-36/37-34
• Safety Statements: 45-38-36/37/39-28A-26-28-27
• RIDADR: 2922
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 3288-04-8(Hazardous Substances Data)

Usage

Chemical Properties

clear light yellow liquid

General Description

IR and Raman spectral measurements of liquid samples of 2-methoxyphenyl isothiocyanate have been investigated.

InChI:InChI=1/C8H7NOS/c1-10-8-5-3-2-4-7(8)9-6-11/h2-5H,1H3

Upstream product

• 1226-64-8 1,3-bis-(2-methoxy-phenyl)-thiourea 
• 463-71-8 thiophosgene 
• 90-04-0 2-methoxy-phenylamine 
• 248279-10-9 N,N'-bis-(2-methoxy-phenyl)-S-methyl-isothiourea 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 590-28-3 potassium cyanate 
• 56676-49-4 2-mercapto-3-(o-methoxyphenyl)-4-thiazolidone 
• 1075256-86-8 3-(2-methoxyphenyl)-5-(2-oxo-2-phenylethyl)-2-thioxo-1,3-thiazolidin-4-one 
• 75-15-0 carbon disulfide 
• 53662-51-4 (2-methoxy-phenyl)-dithiocarbamic acid ; compound with triethylamine 
• 110837-92-8 C₂₆H₂₅AsN₂O₂ 
• 74467-01-9 2-methoxybenzohydroximoyl chloride 
• 854902-49-1 (2-methoxy-phenyl)-dithiocarbamic acid methyl ester 
• 6160-65-2 1,1'-Thiocarbonyldiimidazole 

Downstream Products

• 103151-15-1 (4,5-dihydro-thiazol-2-yl)-(2-methoxy-phenyl)-amine 
• 1226-64-8 1,3-bis-(2-methoxy-phenyl)-thiourea 
• 516458-14-3 1-benzoyl-4-(2-methoxy-phenyl)-thiosemicarbazide 
• 108838-82-0 N-[[(2-methoxyphenyl)amino]thioxomethyl]-4-methylphenylsulfonamide 
• 2741-07-3 N-ethyl-N'-(2-methoxy-phenyl)-thiourea 
• 1219-02-9 N-(o-methoxyphenyl)-N'-phenylthiourea 
• 905481-43-8 hydrazine-N,N'-bis-carbothioic acid di-o-anisidide 
• 859785-61-8 N'-isopropyl-N'''-(2-methoxy-phenyl)-N,N''-p-phenylene-bis-thiourea 
• 857977-58-3 N'-butyl-N'''-(2-methoxy-phenyl)-N,N''-p-phenylene-bis-thiourea 
• 27779-18-6 (5,6-dihydro-4H-[1,3]thiazin-2-yl)-(2-methoxy-phenyl)-amine 
• 135-62-6 Naphthol AS-OL 
• 109868-54-4 3-(2-methoxy-phenylthiocarbamoyl)-carbazic acid ethyl ester 
• 40207-02-1 4-(o-methoxyphenyl)thiosemicarbazide 
• 22007-34-7 (2-methoxy-phenyl)-thiocarbamic acid O-ethyl ester 

Relevant articles and documents

Microwave mediated synthesis of 2-aminooxazoles

A microwave mediated synthesis of 2-aminooxazoles at 150 °C was developed, providing products with a variety of functional groups. The reaction takes 5 min and provides product with a simple precipitation at moderate to good yields without the need for recrystallization or flash chromatography.

Direct, Microwave-Assisted Synthesis of Isothiocyanates

A microwave-assisted desulfuration of readily available dithiocarbamates, formed in situ from primary amines, leading to target isothiocyanates has been developed. This efficient protocol provides a rapid, environmentally benign route to aliphatic and aromatic isothiocyanates.

CYCLOALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR

Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures:(I) (II) where the definitions of the variables are provided herein.