151824-81-6

Basic information

• Product Name: 5-(4-Salicyloylpiperazin-1-yl)-2-nitroaniline
• Synonyms: 5-(4-Salicyloylpiperazin-1-yl)-2-nitroaniline
• CAS NO: 151824-81-6
• Molecular Weight: 342.354
• Mol File: 151824-81-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(4-Salicyloylpiperazin-1-yl)-2-nitroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-Salicyloylpiperazin-1-yl)-2-nitroaniline(151824-81-6)
• EPA Substance Registry System: 5-(4-Salicyloylpiperazin-1-yl)-2-nitroaniline(151824-81-6)

Safety Data

• Hazardous Substances Data: 151824-81-6(Hazardous Substances Data)

Upstream product

• 69-72-7 salicylic acid 
• 96103-52-5 2-nitro-5-piperazin-1-yl-phenylamine 
• 1441-87-8 salicyloyl chloride 
• 99841-06-2 N¹-Salicyloylpiperazine 
• 1635-61-6 5-chloro-2-nitroaniline 

Downstream Products

• 151824-78-1 5-(4-Salicyloylpiperazin-1-yl)-1,2-phenylenediamine 

Relevant articles and documents

Synthesis and potential anthelmintic activity of methyl-5-(4-salicyloyl-piperazin-1-yl)-benzimidazole-2-carbamates

A series of methyl-5-(4-salicyloyl-piperazin-1-yl)-benzimidazole-2-carbamates (IX) has been prepared. 5-(4-salicyloyl-piperazin-1-yl)-2-nitro anilines (VII) have been synthesized starting from 5-piperazino-2-nitro anilines and salicyloyl chlorides. Catalytic reduction of VII with Pd/C, followed by treatment with 1,3-dicarbomethoxy-S-methyl isothiourea, yielded the corresponding carbamates (IX), the anthelmintic activity of which was studied. Compound IX(a) significantly reduced the numbers of preadults, adults and encysted T. spiralis larvae in experimental mice.