15183-75-2

Basic information

• Product Name: Phenol, 2-nitro-4-[(trifluoromethyl)sulfonyl]-
• CAS NO: 15183-75-2
• Molecular Formula: C7H4F3NO5S
• Molecular Weight: 271.174
• Mol File: 15183-75-2.mol

Chemical Properties

• CAS DataBase Reference: Phenol, 2-nitro-4-[(trifluoromethyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-nitro-4-[(trifluoromethyl)sulfonyl]-(15183-75-2)
• EPA Substance Registry System: Phenol, 2-nitro-4-[(trifluoromethyl)sulfonyl]-(15183-75-2)

Safety Data

• Hazardous Substances Data: 15183-75-2(Hazardous Substances Data)

Upstream product

• 432-84-8 4-Hydroxyphenyltrifluoromethylsulphone 
• 461-84-7 (4-trifluoromethylthio)phenol 
• 1550-27-2 1-chloro-2-nitro-4-[(trifluoromethyl)sulfonyl]benzene 
• 102-82-9 tributyl-amine 

Downstream Products

• 1616679-29-8 3-ethylsulfonyl-N-[2-hydroxy-5-(trifluoromethylsulfonyl)phenyl]picolinamide 
• 69245-43-8 2-amino-4-((trifluoromethyl)sulfonyl)phenol 

Relevant articles and documents

METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLSULFONYL)PHENOL COMPOUND

A compound represented by formula (4): can be produced by adding a heterogeneous transition metal catalyst to a solution containing a compound represented by formula (3): obtained by performing a nitration reaction by adding a nitrating agent to a solution containing a compound represented by formula (2): obtained by oxidizing a compound represented by formula (1): with hydrogen peroxide in the presence of sodium tungstate and a saturated C8 carboxylic acid, then adding water to the resultant mixture, and separating the resultant solution.

METHOD FOR PRODUCING PHENOLIC COMPOUND

Provided is a method for producing a compound represented by formula (2-b), which is useful as an intermediate for producing agricultural chemicals. The method includes a step for obtaining a compound represented by formula (2-a) by oxidizing the compound represented by formula (1) with hydrogen peroxide in the presence of sulfuric acid and/or a C1-6 alkanesulfonic acid that may be halogen-substituted and in the presence of a C2-12 aliphatic carboxylic acid and/or sulfolane. The method also includes a step for obtaining a compound represented by formula (2-b) by nitrating a compound represented by formula (2-a) in the presence of sulfuric acid and/or a C1-6 alkanesulfonic acid that may be halogen-substituted.

FUSED OXAZOLE COMPOUNDS AND USE THEREOF FOR PEST CONTROL

Disclosed is a compound represented by formula (1): wherein A1 represents N(O)p or CH; A2 represents N(O)q; R1 represents a trifluoromethyl group, a halogen atom or a hydrogen atom; R2 represents a C1-C3 perfluoroalkyl group, p represents 0 or 1; q represents 0 or 1; n represents 0, 1 or 2; and m represents 0, 1 or 2, having an excellent controlling effect on pests.

COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE

Compounds of formula (I) or a salt thereof are provided: wherein R4, R5, R6, Q, A, Y and R are as defined in the description. Uses of the compounds as medicaments and in the manufacture of medicaments for treating psychotic disorders, cognitive impairments and Alzheimer's Disease are disclosed. The invention further discloses pharmaceutical compositions comprising the compounds.

REACTIONS OF SUBSTITUTED HALOGENOBENZENES WITH TRIBUTYLAMINE

The reactions of 2,4-dinitrohalobenzenes and 2-nitro-4-trifluoromethylsulfonylchlorobenzene with tributylamine in DMFA lead to the formation of two products, i.e., substituted N,N-dibutylanilines and phenols.The reactions occur with an induction period, which disappears with increase in temperature, and with fractional orders in the reagents.The effective activation was determined by means of the transformation coefficients.The ordes of mobility of the halogens in the reaction of 2,4-dinitrohalogenobenzenes with tributylamine is Br >= Cl > F.The effect of substituents on the mobility of the chlorine corresponds to their accepting characteristics: SO2CF3 > NO2.