69245-43-8

Usage

Physical State

White to off-white solid

Solubility

Sparingly soluble in water

Applications

Intermediate in the synthesis of pharmaceuticals and agrochemicals
Possesses anti-inflammatory and antioxidant properties

Environmental Impact

Considered a potential environmental hazard due to its trifluoromethylsulfonyl group
Subject to strict handling and disposal regulations

Versatility

Suitable for medicinal and research purposes
Has a range of potential applications in various fields.

Upstream product

• 15183-75-2 2-nitro-4-(trifluoromethylsulfonyl)phenol 
• 461-84-7 (4-trifluoromethylthio)phenol 
• 432-84-8 4-Hydroxyphenyltrifluoromethylsulphone 
• 24541-44-4 2-azidophenol 
• 2926-29-6 Langlois reagent 

Downstream Products

• 1134197-90-2 2-({1-[trans-1-methyl-4-(propyloxy)cyclohexyl]-4-piperidinyl}amino)-4-[(trifluoromethyl)sulfonyl]phenol 
• 1616679-29-8 3-ethylsulfonyl-N-[2-hydroxy-5-(trifluoromethylsulfonyl)phenyl]picolinamide 
• 64507-05-7 5-chloroindole-2-carbonyl chloride 

Relevant academic research and scientific papers

METHOD FOR PRODUCING 2-AMINO-4-SUBSTITUTED PHENOL

A compound represented by formula (3): (wherein R1 represents a C1-C6 alkyl group optionally having one or more halogen atoms, R2 represents a C1-C6 alkyl group, and m represents an integer of 0 to 3) can be produced by reacting a C1

METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLSULFONYL)PHENOL COMPOUND

A compound represented by formula (4): can be produced by adding a heterogeneous transition metal catalyst to a solution containing a compound represented by formula (3): obtained by performing a nitration reaction by adding a nitrating agent to a solution containing a compound represented by formula (2): obtained by oxidizing a compound represented by formula (1): with hydrogen peroxide in the presence of sodium tungstate and a saturated C8 carboxylic acid, then adding water to the resultant mixture, and separating the resultant solution.

METHOD FOR PRODUCING PHENOLIC COMPOUND

Provided is a method for producing a compound represented by formula (2-b), which is useful as an intermediate for producing agricultural chemicals. The method includes a step for obtaining a compound represented by formula (2-a) by oxidizing the compound represented by formula (1) with hydrogen peroxide in the presence of sulfuric acid and/or a C1-6 alkanesulfonic acid that may be halogen-substituted and in the presence of a C2-12 aliphatic carboxylic acid and/or sulfolane. The method also includes a step for obtaining a compound represented by formula (2-b) by nitrating a compound represented by formula (2-a) in the presence of sulfuric acid and/or a C1-6 alkanesulfonic acid that may be halogen-substituted.

FUSED OXAZOLE COMPOUNDS AND USE THEREOF FOR PEST CONTROL

Disclosed is a compound represented by formula (1): wherein A1 represents N(O)p or CH; A2 represents N(O)q; R1 represents a trifluoromethyl group, a halogen atom or a hydrogen atom; R2 represents a C1-C3 perfluoroalkyl group, p represents 0 or 1; q represents 0 or 1; n represents 0, 1 or 2; and m represents 0, 1 or 2, having an excellent controlling effect on pests.

COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE

Compounds of formula (I) or a salt thereof are provided: wherein R4, R5, R6, Q, A, Y and R are as defined in the description. Uses of the compounds as medicaments and in the manufacture of medicaments for treating psychotic disorders, cognitive impairments and Alzheimer's Disease are disclosed. The invention further discloses pharmaceutical compositions comprising the compounds.