15185-52-1Relevant academic research and scientific papers
Oxoketene Dithiols: Synthesis of Some Heterocycles as Antimicrobials Utilizing Shrimp Chitin as a Natural Catalyst
Zayed, Salem E.,El-Maghraby, Awatef M.,Hassan, Entesar A.
, p. 1682 - 1698 (2015/10/29)
1, 2-dithiol 3-thione derivatives, as starting materials, were subjected to cycloaddition reactions in the presence of the dried outer shell of shrimp (chitin), under different reaction conditions to produce the 1, 3-dithiole-2-ylidene system. On treating 4-bromo dithiol 3-one, with dimethyl ester of acetylene dicarboxylic acid the bromo oxothiafulvene was produced. Further addition of DMAD to bromotrithiafulvene afforded the spiro bromo derivative. Trithiones and trithiafulvenes were also added to quinones, cyclohexadiene and cyclopentadiene monomer, and the corresponding adducts were produced through 1,3-dipole cycloaddition reactions. On testing some of the products against the isolated micro-organisms from sugar cane factory, the inhibition zones at concentration 1 × 10-6 were found. Products (2, 6, 9, 16, 23, 25, and 26) showed high activities against Bacillus sub., E.Coli and Asper. Niger.
Thiafulvenes and thiafulvalenes in organic chemistry: Synthesis and study its behavior towards some chemical reagents
Zayed, Salem E.,Hassan, M. Ezel-Dean,Ragab, Rawia
, p. 2205 - 2216 (2008/02/10)
Trithiafulvenes were prepared through cycloaddition of 3-thioxo-1,2- dithioles to several electrophilic alkenes and alkynes. Treatments of the product with phenyl-hydrazine and malononitrile afforded the hydrazone and the dinitrilene derivatives respectiv
Ketoken gem-dithiols and trithiones: Synthesis and study of the behavior towards dipole reagents; Synthesis of some nitrogen heteroaromatics
Zayed, Salem E.
, p. 7 - 13 (2007/10/03)
The behavior of ketoken gem-dithiols towards active methylene and methyl groups resulted in the formation of thiopyrano-dihydrocaumarine derivatives IIIa,b via cyclocondensation reaction between substituted 4-dihydrocyclohexanone Ia.b. N-phenylpyrazoline
