151937-11-0Relevant articles and documents
SYNTHESES OF A REGIOISOMER OF N-PYRIMIDIN-5-YL)ETHYL>BENZOYL>-L-GLUTAMIC ACID (LY231514), AN ACTIVE THYMIDYLATE SYNTHASE INHIBITOR AND ANTITUMOR AGENT
Taylor, Edward C.,Young, Wendy B.,Chaudhari, Rajendra,Patel, Hemantkumar H.
, p. 1897 - 1908 (2007/10/02)
Two independent routes to N-pyrimidin-6-yl)ethyl>benzoyl>-L-glutamic acid, a regioisomer of the potent TS inhibitor and antitumor agent LY231514, are described.Preliminary in vitro cell culture evaluation has show