151950-83-3

Upstream product

• 1745-81-9 o-Allylphenol 
• 151950-94-6 1-tert-butyldimethylsilyloxy-2-(2-propenyl)benzene 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 327155-45-3 3-(2-((tert-butyldimethylsilyl)oxy)phenyl)propan-1-ol 

Downstream Products

• 186352-42-1 N-formyl-6-[3-(2-hydroxyphenyl)propyl]-1,2,3,4-tetrahydropyridine 
• 186352-43-2 Trifluoro-methanesulfonic acid 2-[3-(1-formyl-1,4,5,6-tetrahydro-pyridin-2-yl)-propyl]-phenyl ester 
• 151950-87-7 Trifluoro-methanesulfonic acid 2-[(Z)-6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-hex-4-enyl]-phenyl ester 
• 151950-98-0 tert-Butyl-[(E)-2-((S)-1-methyl-1,2,3,4-tetrahydro-naphthalen-1-yl)-vinyloxy]-diphenyl-silane 

Relevant academic research and scientific papers

Enantioselective copper-catalyzed intramolecular phenolic O-H bond insertion: Synthesis of chiral 2-carboxy dihydrobenzofurans, dihydrobenzopyrans, and tetrahydrobenzooxepines

Efficient: A copper-catalyzed enantioselective intramolecular insertion of carbenoids into phenolic O-H bonds has been developed. This method can be used for the synthesis of the title compounds in high yields and excellent enantioselectivities under mild and neutral conditions (see scheme). NaBAr F=sodium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate. Copyright

Intramolecular Enantioselective Palladium-Catalyzed Heck Arylation of Cyclic Enamides

Palladium-catalyzed intramolecular cyclization of N-formyl-6--1,2,3,4-tetrahydropyridine (1a) and N-formyl-6--1,2,3,4-tetrahydropyridine (1b) in the presence of AsPh3 resulted in formation of the spiro compounds N-formyl-3,3',4,4'-tetrahydrospiro (2a) and N-formyl-3',4'-dihydrospiro (2b), respectively, and in the presence of PPh3 and TlOAc in the spiro compounds N-formyl-3,4,5',6'-tetrahydrospiro (3a) and N-formyl-5',6'-dihydrospiro (3b), respectively.Cyclization of N-formyl-6-(3-phenyl>propyl)-1,2,3,4-tetrahydropyridine (7) in presence of a chiral (phosphinoaryl)oxazoline ((S)-8) resulted in formation of (R)-3a and (R)-N-formyl-1',3,4,6'-tetrahydrospiro ((R)-6a) in high enantiomeric excesses, 87 percent and >99percent, respectively, and in good yield.The oxazoline ligand (S)-8 furnished higher enantiomeric excesses and improved regioselectivities than (R)-BINAP.