15196-73-3 Usage
Description
4-TERT-BUTYLBENZO-15-CROWN-5, also known as t-butylcalix[4]arene[4]cryptand, is a synthetic macrocyclic polyether compound belonging to the class of crown ethers. It features a cavity formed by 15 atoms that can complex with cations, making it a versatile tool for molecular recognition, separation processes, and various applications in chemical and biological systems.
Uses
Used in Organic Synthesis:
4-TERT-BUTYLBENZO-15-CROWN-5 is used as a phase-transfer catalyst for facilitating reactions between organic and inorganic compounds. Its ability to complex with cations enhances the solubility and reactivity of reactants, improving the efficiency and selectivity of organic synthesis processes.
Used in Ion-Selective Electrode Materials:
In the field of analytical chemistry, 4-TERT-BUTYLBENZO-15-CROWN-5 is used as a material for ion-selective electrodes. Its selective binding properties allow for the accurate detection and measurement of specific cations in various samples, providing a reliable method for ion analysis.
Used in Pharmaceutical and Medicinal Chemistry:
4-TERT-BUTYLBENZO-15-CROWN-5 is utilized in drug delivery systems to improve the solubility, stability, and bioavailability of pharmaceutical compounds. Its cation-complexing ability enables the controlled release and targeted delivery of drugs, enhancing their therapeutic efficacy and reducing side effects.
Used in Molecular Recognition and Separation Processes:
In chemical and biological systems, 4-TERT-BUTYLBENZO-15-CROWN-5 is employed for molecular recognition and separation processes. Its selective binding properties allow for the efficient separation of target molecules from complex mixtures, facilitating the purification and analysis of various compounds.
Used in Chemical Industry:
4-TERT-BUTYLBENZO-15-CROWN-5 is used as a catalyst or additive in various chemical processes, enhancing reaction rates and improving product yields. Its cation-complexing ability can also be utilized for the selective extraction and separation of specific compounds from mixtures, streamlining industrial processes.
Used in Environmental Applications:
4-TERT-BUTYLBENZO-15-CROWN-5 can be employed for the removal of heavy metal ions from contaminated water and soil samples. Its selective binding properties enable the efficient capture and sequestration of toxic metal ions, mitigating their environmental impact and facilitating remediation efforts.
Check Digit Verification of cas no
The CAS Registry Mumber 15196-73-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,1,9 and 6 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 15196-73:
(7*1)+(6*5)+(5*1)+(4*9)+(3*6)+(2*7)+(1*3)=113
113 % 10 = 3
So 15196-73-3 is a valid CAS Registry Number.
15196-73-3Relevant articles and documents
Preparation of benzo- and polybenzocrown ethers by macrocyclization reactions
Hanes, Robert E.,Lee, Jong Chan,Ivy, Sheryl N.,Palka, Anna,Bartsch, Richard A.
, p. 238 - 248 (2012/11/07)
Macrocyclization of crown ethers and their methods of preparation were explored. We present a robust, scalable method for the preparation of these macrocycles. Additionally, the effect of changing the structures of the precursors was explored to determine whether the 'cut' of bisphenol and dimesylate influenced the course of the reaction as measured by the yield. Further, using catechol derivatives, the method was used for the preparation of monobenzocrown ethers. Interestingly, for the preparation of monobenzocrown ethers, [2+2] adducts were discovered to be significantly contaminating the products. Dimesylates were chosen as the leaving group due to their ease or preparation and the ability to use the unpurified products with no apparent impact on the macrocyclization.
ALKYLATION OF BENZOCROWN ETHERS BY CERTAIN ALCOHOLS
Kotlyar, S. A.,Klimova, E. I.
, p. 1313 - 1314 (2007/10/02)
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4'-tert-AlkylbenzoCrown-5-Ether. Syntheses and Complexes with Potassium Thiocyanate
Beger, J.,Meerbote, M.
, p. 2 - 9 (2007/10/02)
The title compounds 4 are synthesized either by alkylation of pyrocatechole 1 in 4-position and followed by ring closure with 1,11-dichloro-3,6,9-trioxaundecane or by alkylation of benzo-crown-5 3.In most cases the way first mentioned gives better results.Analytical samples of the alkylated benzocrown-5 ethers 4 are obtained through complexing with KSCN.Physical data and 1H-n.m.r.-spectra of 5 new pyrocatecholes 2 and 6 new benzocrown-5 ethers 4 are given.
