15197-44-1

Upstream product

• 15719-28-5 2-Naphthylphenylmethylsilyl-2-phenyl-1,3-dithian 
• 53178-41-9 2-lithio-2-phenyl-1,3-dithiane 
• 960-82-7 S(-)-methyl-α-naphthyl-phenyl-chlorosilane 
• 115691-12-8 R-(-)-methyl-α-naphthyl-phenylsilyl phenyl thioketone 

Downstream Products

• 642-28-4 (R)-naphthalen-1-yl-phenyl-methanol 
• 115691-12-8 R-(-)-methyl-α-naphthyl-phenylsilyl phenyl thioketone 

Relevant academic research and scientific papers

1,2-diastereoselection induced by chiral silicon in the addition of Grignard reagents to acylsilanes

The reaction of acylsilanes 1 with Grignard reagents gives the diastereomeric α-hydroxysilanes 3. The level of asymmetric induction depends on the nature of R1 and R2. Good results were obtained for R1=t-Bu, R2=

Asymmetric Induction by Chiral Silicon. Synthesis and Electrophilic Reactivity towards Dienes and Carbanions of R-(-)-Methyl-α-naphthyl-phenylsilyl Phenyl Thioketone

The title compound was prepared by acid catalysed reaction of the corresponding ketone with hydrogen sulphide, and its ability to transfer chirality to the carbon α to silicon in reactions with buta-1,3-diene and methyl-lithium was tested; good levels of