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Silane, chloromethyl-1-naphthalenylphenyl-, (S)-, also known as (S)-(+)-1-(Chloromethyl)-1'-naphthalenyl-1,1'-biphenyl-2-ylsilane, is a chiral organosilicon compound with the molecular formula C19H17ClSi. It is a colorless to pale yellow liquid and is soluble in common organic solvents. Silane, chloromethyl-1-naphthalenylphenyl-, (S)- is primarily used as a reagent in organic synthesis, particularly in the preparation of chiral ligands and catalysts for asymmetric reactions. The (S)-enantiomer is one of two possible enantiomers, which differ in the spatial arrangement of their atoms, and is often preferred due to its specific stereochemical properties. The compound's unique structure, featuring a silicon atom bonded to a chiral biphenyl group and a chloromethyl group, makes it a valuable building block in the development of new chiral materials and pharmaceuticals.

960-82-7

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960-82-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 960-82-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,6 and 0 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 960-82:
(5*9)+(4*6)+(3*0)+(2*8)+(1*2)=87
87 % 10 = 7
So 960-82-7 is a valid CAS Registry Number.

960-82-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name rac-methyl(1-naphthyl)phenylchlorosilane

1.2 Other means of identification

Product number -
Other names chloro(1-naphthyl)phenylmethylsilane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:960-82-7 SDS

960-82-7Relevant academic research and scientific papers

Iron-catalyzed chlorination of silanes

Savela, Risto,Zawartka, Wojciech,Leino, Reko

experimental part, p. 3199 - 3206 (2012/06/04)

A simple and highly efficient iron-catalyzed method for the chlorination of silanes has been developed. By use of 0.5-2% of the Fe(III)-based catalyst FeCl3 or Fe(acac)3 in the presence of 1-1.5 equiv of acetyl chloride as the chlorine donor, a large number of silanes, alkoxysilanes, and silanols were converted to the corresponding chlorosilanes in 50-93% yields. In contrast to earlier reported methods often suffering from expensive catalysts or use of stoichiometric metal salts, hazardous reagents, and reaction conditions, the presently described methodology allows benign reaction conditions and simple workup while using only catalytic amounts of a readily available and economically viable iron catalyst.

Stereoselective synthesis of optically active disilanes and selective functionalization by the cleavage of silicon-naphthyl bonds with bromine

Suzuki, Keigo,Kawakami, Yusuke,Velmurugan, Devadasan,Yamane, Takashi

, p. 5383 - 5389 (2007/10/03)

Optically active disilanes with one chiral silicon center, (R)-1,2-dimethyl-1-(naphth-1-yl)-1,2,2-triphenyldisilane and (R)-1,2,2 -trimethyl-2-(4-methoxynaphth-1-yl)-1-(naphth-1-yl)-1-phenyldisilane, were obtained by the reaction of (S)-methyl(naphth-1-yl

1,2-diastereoselection induced by chiral silicon in the addition of Grignard reagents to acylsilanes

Bonini, Bianca F.,Masiero, Stefano,Mazzanti, Germana,Zani, Paolo

, p. 6801 - 6804 (2007/10/02)

The reaction of acylsilanes 1 with Grignard reagents gives the diastereomeric α-hydroxysilanes 3. The level of asymmetric induction depends on the nature of R1 and R2. Good results were obtained for R1=t-Bu, R2=

THE NATURE AND CONSEQUENCES OF THE INTERACTION OF PHOSPHORYL NUCLEOPHILES WITH A TRIORGANOSILYL CHLORIDE

Chojnowski, J.,Cypryk, M.,Michalski J.,Wozniak, L.

, p. 275 - 282 (2007/10/02)

In order to throw light on the possible role of positively charged tetra-coordinate silicon intermediates in the racemization of α-NpPhMeSiCl (1) induced by uncharged nucleophiles two sets of kinetic studies have been carried out.In the first the rates of two reactions namely racemization of 1 catalysed by (PhO)2(Me3SiO)P=O (2) and transsilylation of 2 with 1, which take place together and are believed to involve the same intermediate were determined; the transsilylation was found to be faster than the racemization, and involved transient formation of an optically active product.In the second the racemization of 1 catalysed by HMPT in various CCl4/CH2Cl2 mixtures was studied; the rate was found to increase markedly with increase in the dielectric constant of the medium.The results of both sets of experiments were consistent with a mechanism involving a silyloxyphosphonium cation intermediate.

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