151982-60-4

Upstream product

• 2199-44-2 3,5-dimethyl-2-ethoxycarbonyl-1H-pyrrole 
• 403-43-0 4-fluorobenzoyl chloride 

Downstream Products

• 147434-50-2 [6-(4-Fluoro-benzyl)-5,7-dimethyl-3-oxo-1-thioxo-1H-pyrrolo[1,2-c]imidazol-2-yl]-acetic acid ethyl ester 
• 147434-13-7 [6-(4-Fluoro-benzyl)-5,7-dimethyl-1,3-dioxo-1H-pyrrolo[1,2-c]imidazol-2-yl]-acetic acid ethyl ester 
• 147433-87-2 {[4-(4-Fluoro-benzyl)-3,5-dimethyl-1H-pyrrole-2-carbonyl]-amino}-acetic acid ethyl ester 
• 147433-66-7 4-(4-Fluoro-benzyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid 
• 151982-69-3 4-(4-Fluoro-benzyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

PYRROLE COMPOUND

Provided is a highly safe and effective compound represented by the following general formula (1) or a salt thereof which acts on tubulin and has an anticancer effect, wherein Ar represents an aryl group or a heteroaryl group; Z1, Z2

Synthesis and aldose reductase inhibitory activity of acetic acid derivatives of pyrrolo[1,2-c]imidazole

Various acetic acid derivatives of pyrrolo[1,2-c]imidazole were prepared and evaluated for aldose reductase inhibitory activity. Most of the compounds inhibited aldose reductase isolated from rat lens in vitro and decreased sorbitol formation in sciatic n