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"4,5,6,7-Tetrachloro-3,6-dihydroxy-2,4,5,7-tetraiodospiro(isobenzofuran-1(3H),9(9H)-xanthen)-3-one" is a complex organic compound characterized by its unique molecular structure. It features a spiro ring system, which is a fused ring system where two rings share a common atom. In this case, the spiro system consists of an isobenzofuran and a xanthen ring. The compound is further defined by the presence of four chlorine atoms and four iodine atoms, which are distributed across the molecule, and two hydroxyl groups. The tetrachloro and tetraiodo substitutions, along with the dihydroxy functionality, contribute to the compound's chemical properties and potential applications, which may include areas such as imaging, sensing, or as a precursor in the synthesis of other complex molecules. The specific arrangement of these functional groups and the spiro structure make 4,5,6,7-Tetrachloro-3,6-dihydroxy-2,4,5,7-tetraiodospiro(isobenzofuran-1(3H),9(9H)-xanthen)-3-one a subject of interest in organic chemistry and material science.

152-74-9

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152-74-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 152-74-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,5 and 2 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 152-74:
(5*1)+(4*5)+(3*2)+(2*7)+(1*4)=49
49 % 10 = 9
So 152-74-9 is a valid CAS Registry Number.

152-74-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name bengal rose B

1.2 Other means of identification

Product number -
Other names 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[2-benzofuran-3,9'-xanthene]-1-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:152-74-9 SDS

152-74-9Relevant academic research and scientific papers

Rose Bengal analogs and vesicular glutamate transporters (VGLUTs)

Pietrancosta, Nicolas,Kessler, Albane,Favre-Besse, Franck-Cyril,Triballeau, Nicolas,Quentin, Thomas,Giros, Bruno,Mestikawy, Salah El,Acher, Francine C.

, p. 6922 - 6933 (2010)

Vesicular glutamate transporters (VGLUTs) allow the loading of presynaptic glutamate vesicles and thus play a critical role in glutamatergic synaptic transmission. Rose Bengal (RB) is the most potent known VGLUT inhibitor (K i 25 nM); therefore we designed, synthesized and tested in brain preparations, a series of analogs based on this scaffold. We showed that among the two tautomers of RB, the carboxylic and not the lactonic form is active against VGLUTs and generated a pharmacophore model to determine the minimal structure requirements. We also tested RB specificity in other neurotransmitter uptake systems. RB proved to potently inhibit VMAT (Ki 64 nM) but weakly VACHT (Ki >9.7 μM) and may be a useful tool in glutamate/acetylcholine co-transmission studies.

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