152035-97-7Relevant academic research and scientific papers
Convenient Synthesis of Alcohol O-Hemiesters using Isopropenyl Esters as Acylating Reagents: Synthesis of Hydrophilic Oxaunomycin 10-O-Hemiester Derivatives
Kita, Yasuyuki,Maeda, Hiroshi,Takahashi, Fumie,Fukui, Seiji
, p. 2639 - 2650 (2007/10/02)
Various types of alcohol O-hemiesters 7a-m were synthesized conveniently in good yield by reaction with isopropenyl esters 4a-f in the presence of a catalytic amount of conc.H2SO4 or toluene-p-sulfonic acid followed by selective deprotection of the terminal esters.This method was applied to a preparation of hydrophilic oxaunomycin 10-O-hemiester derivatives 14a,b and 19a-c.
