152126-32-4 Usage
Uses
Used in Pharmaceutical Research and Development:
2-Pyridinecarboxamide,3-fluoro-(9CI) is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structural features and potential biological activities make it a valuable asset in the development of new drugs with improved efficacy and selectivity.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-Pyridinecarboxamide,3-fluoro-(9CI) is utilized as a building block for the design and synthesis of novel bioactive molecules. Its fluorine substitution at the 3-position of the pyridine ring can influence the physicochemical properties, such as lipophilicity and metabolic stability, which are crucial for drug discovery and optimization.
Used in Chemical Synthesis:
2-Pyridinecarboxamide,3-fluoro-(9CI) serves as a versatile synthetic intermediate for the preparation of a wide range of chemical compounds, including agrochemicals, dyes, and other specialty chemicals. Its reactivity and functional group compatibility make it a valuable component in various synthetic routes.
Used in Fluorine Chemistry:
In the realm of fluorine chemistry, 2-Pyridinecarboxamide,3-fluoro-(9CI) is employed as a precursor for the synthesis of fluorinated pyridine derivatives. The introduction of fluorine atoms can significantly alter the electronic and steric properties of the molecule, leading to new chemical entities with unique properties and potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 152126-32-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,2,1,2 and 6 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 152126-32:
(8*1)+(7*5)+(6*2)+(5*1)+(4*2)+(3*6)+(2*3)+(1*2)=94
94 % 10 = 4
So 152126-32-4 is a valid CAS Registry Number.
152126-32-4Relevant academic research and scientific papers
Ashwood, Michael S.,Alabaster, Ramon J.,Cottrell, Ian F.,Cowden, Cameron J.,Davies, Antony J.,Dolling, Ulf H.,Emerson, Khateeta M.,Gibb, Andrew D.,Hands, David,Wallace, Debra J.,Wilson, Robert D.
, p. 192 - 200 (2004)
A scaleable route to 2-{3-[(2,2-difluoro-2-(2-pyridyl)ethyl)-animo]-6- chloro-2-oxohydropyrazinyl}-N-(3-fluoro(2-pyridyl))-methyl]acetamide 1 is described in which various scaleup issues were addressed to provide a safe, efficient, and robust route for th
PROCESS FOR THE PREPARATION OF PYRAZINONE THROMBIN INHIBITOR AND ITS INTERMEDIATES
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Page/Page column 5, (2011/05/08)
Improved process for the preparation of 3-fluoro-2-pyridylmethyl-3-(2,2-difluoro-2-(2-pyridyl)ethylamino)-6-chloropyrazin-2-one-1-acetamide of formula (I) and its intermediates is provided.
PROCESS FOR THE PREPARATION OF PYRAZINONE THROMBIN INHIBITOR AND ITS INTERMEDIATES
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Page/Page column 10, (2011/06/11)
An improved process for the preparation of 3-fruoro-2-pyridylmethyl-3-(2,2- difluoro-2-(2-pyridyl)ethylamino)-6-chloropyrazin-2-one- 1 -acetamide and its intermediates.
