152169-40-9

Upstream product

• 152169-36-3 ethyl 6-(N-ethoxycarbonylamino)-2-hydroxybenzoate 
• 146463-87-8 ethyl 2-(N-ethoxycarbonyl-N-pivaloyl)amino-6-(tetrahydropyran-2-yloxy)benzoate 
• 107-30-2 chloromethyl methyl ether 
• 152169-39-6 ethyl 6-(N-ethoxycarbonylamino)-3-fluoro-2-hydroxybenzoate 

Downstream Products

• 180595-83-9 ethyl 6-(N-ethoxycarbonyl-N-pivaloylamino)-3-fluoro-2-methoxymethoxybenzoate 
• 152835-80-8 N-(2-{3-[4-(2,2-Dimethyl-propionylamino)-phenyl]-3-oxo-propionyl}-4-fluoro-3-methoxymethoxy-phenyl)-2,2-dimethyl-propionamide 
• 152835-56-8 N-{2-[4-(2,2-Dimethyl-propionylamino)-phenyl]-8-fluoro-4-oxo-4H-chromen-5-yl}-2,2-dimethyl-propionamide 

Relevant academic research and scientific papers

Design and synthesis of potent antitumor 5,4'-diaminoflavone derivatives based on metabolic considerations

Recently, we reported that 5,4'-diaminoflavone (1) exhibits potent and specific growth-inhibitory activity against the estrogen receptor (ER)- positive human breast cancer cell line MCF-7. However, when compound 1 was incubated with S-9 mix, its metabolit