152169-36-3Relevant academic research and scientific papers
Design and synthesis of potent antitumor 5,4'-diaminoflavone derivatives based on metabolic considerations
Akama, Tsutomu,Ishida, Hiroyuki,Shida, Yasushi,Kimura, Uichiro,Gomi, Katsushige,Saito, Hiromitsu,Fuse, Eiichi,Kobayashi, Satoshi,Yoda, Nobuyuki,Kasai, Masaji
, p. 1894 - 1900 (1997)
Recently, we reported that 5,4'-diaminoflavone (1) exhibits potent and specific growth-inhibitory activity against the estrogen receptor (ER)- positive human breast cancer cell line MCF-7. However, when compound 1 was incubated with S-9 mix, its metabolit
5-aminoflavone derivatives
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, (2008/06/13)
5-Aminoflavone derivatives represented by the formula (I): STR1 wherein R1, R2, R3 and R4 are the same or different and represent hydrogen, substituted or unsubstituted lower alkyl, lower alkenyl, halogen-substi
5-Aminoflavone derivatives, their preparation and their use as antibacterial, anti-estrogenic and/or antitumor agent
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, (2008/06/13)
5-Aminoflavone derivatives represented by the formula (I): wherein R1 and R2 are the same or different and represent hydrogen or substituted or unsubstituted lower alkyl, X represents substituted or unsubstituted lower alkyl, lower alkenyl, lower alkynyl,
