152171-30-7

Upstream product

• 106-54-7 p-Chlorothiophenol 
• 2315-37-9 2-chloro-N,N-dipropylacetamide 
• 152171-32-9 N,N-di-n-propyl-(p-chlorophenylthio)-acetamide 

Downstream Products

• 152171-28-3 N,N-di-n-propyl-(1-benzenesulfonyl-7-methoxy-5-indolinyl)-acetamide 
• 155636-51-4 N,N-di-n-propyl-(p-chlorophenylthio)-(1-benzenesulfonyl-6-benzenesulfonyloxy-5-indolinyl)-acetamide 
• 152171-27-2 N,N-di-n-propyl-(1-benzenesulfonyl-7-methoxy-5-indolinyl)-(p-chlorophenylthio)-acetamide 

Relevant academic research and scientific papers

A direct and versatile synthesis of 5-(2-di-n-propylamino-ethyl)-7-methoxyindole

The Pummerer intermediate generated from 10 with TFAA was trapped intermolecularly in the presence of Lewis acid by the indoline 2 at position 5. Sequential treatment of the resulted compound 3 with Ra-Ni, LiAlH4 and active MnO2 gave compound 6 in high overall yield.