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2,3,4,5-Tetrahydro-3-[(4-methylphenyl)sulfonyl]-1H-3-benzazepin-1-one, commonly known as ramosetron, is a pharmaceutical compound that serves as a selective serotonin 5-HT3 receptor antagonist. It is utilized in the treatment of gastrointestinal disorders, particularly irritable bowel syndrome (IBS), by blocking serotonin receptors in the gut, which in turn alleviates symptoms such as diarrhea and abdominal pain. Ramosetron is recognized for its effectiveness and longer duration of action compared to other medications in its class. It is available for administration in both oral and injectable forms and is generally well-tolerated, with common side effects including constipation, headache, and dizziness.

15218-07-2

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15218-07-2 Usage

Uses

Used in Pharmaceutical Industry:
2,3,4,5-Tetrahydro-3-[(4-methylphenyl)sulfonyl]-1H-3-benzazepin-1-one is used as a medication for the treatment of gastrointestinal disorders, specifically irritable bowel syndrome (IBS), due to its ability to block serotonin receptors in the gut, thereby reducing symptoms like diarrhea and abdominal pain.
Used in Gastroenterology:
In the field of gastroenterology, 2,3,4,5-Tetrahydro-3-[(4-methylphenyl)sulfonyl]-1H-3-benzazepin-1-one is employed as a selective serotonin 5-HT3 receptor antagonist to provide relief from the discomforts associated with IBS and other related gastrointestinal conditions, enhancing the quality of life for affected individuals.
Used in Drug Formulation:
2,3,4,5-Tetrahydro-3-[(4-methylphenyl)sulfonyl]-1H-3-benzazepin-1-one is utilized in the formulation of oral and injectable medications, offering patients a choice in the mode of administration that best suits their needs and preferences, while ensuring effective management of gastrointestinal symptoms.

Check Digit Verification of cas no

The CAS Registry Mumber 15218-07-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,2,1 and 8 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 15218-07:
(7*1)+(6*5)+(5*2)+(4*1)+(3*8)+(2*0)+(1*7)=82
82 % 10 = 2
So 15218-07-2 is a valid CAS Registry Number.
InChI:InChI=1/C17H17NO3S/c1-13-6-8-15(9-7-13)22(20,21)18-11-10-14-4-2-3-5-16(14)17(19)12-18/h2-9H,10-12H2,1H3

15218-07-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(4-methylphenyl)sulfonyl-2,4-dihydro-1H-3-benzazepin-5-one

1.2 Other means of identification

Product number -
Other names 3-[(4-methylphenyl)sulfonyl]-2,3,4,5-tetrahydro-1H-3-benzazepin-1-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15218-07-2 SDS

15218-07-2Relevant academic research and scientific papers

BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE

-

, (2020/10/20)

Compounds for use in treating or preventing human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2, L, W1, W2, X, Y, and Z are as defined herein. Methods associated with the preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

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