152189-67-8Relevant articles and documents
A NEW SYNTHESIS 2-ACYL-1,2,3,6,7,11b-HEXAHYDROPYRAZINOISOQUINOLIN-4-ONES BASED ON N-CYANOMETHYL DERIVATIVES OF 2-PHENYL-ETHYLAMIDES OF ACYLGLYCINES
Shekhter, O. V.,Kuklenkova, O. B.,Sergovskaya, N. L.,Tsizin, Yu. S.
, p. 170 - 173 (2007/10/02)
A new route for the synthesis of 2-acyl-1,2,3,6,7,11b-hexahydropyrazinoisoquinolin-4-ones has been studied which includes a stage in which substituted piperazinones are obtained by reductive cyclization of N-cyanomethyl derivatives of 2-phenylethylamides of acylglycines under influence of Raney alloy in formic acid.