152279-17-9

Basic information

• Product Name: 2-Cyclopentene-1-carboxylicacid,4-amino-,methylester,cis-(9CI)
• Synonyms: 2-Cyclopentene-1-carboxylicacid,4-amino-,methylester,cis-(9CI);Cis-4-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester;ANVYHALMQXHQSG-RITPCOANSA-N
• CAS NO: 152279-17-9
• Molecular Formula: C7H11NO2
• Molecular Weight: 141.17
• Product Categories: CARBOXYLICESTER;AMINOACID
• Mol File: 152279-17-9.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 191.9±40.0 °C(Predicted)
• Appearance: /
• Density: 1.109±0.06 g/cm3(Predicted)
• PKA: 9.66±0.40(Predicted)
• CAS DataBase Reference: 2-Cyclopentene-1-carboxylicacid,4-amino-,methylester,cis-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclopentene-1-carboxylicacid,4-amino-,methylester,cis-(9CI)(152279-17-9)
• EPA Substance Registry System: 2-Cyclopentene-1-carboxylicacid,4-amino-,methylester,cis-(9CI)(152279-17-9)

Safety Data

• Hazardous Substances Data: 152279-17-9(Hazardous Substances Data)

Upstream product

• 344326-33-6 4-aminocyclopent-2-enecarboxylic acid 
• 67-56-1 methanol 
• 79200-56-9 (-)-2-azabicyclo[2.2.1]hept-5-en-3-one 
• 77745-25-6 cis-4-amino-2-cyclopentenecarboxylic acid methyl ester hydrochloride 
• 157732-11-1 (1R,4S)-N-acetoxymethyl-2-azabicyclo[2.2.1]hept-5-en-3-one 
• 183074-62-6 N-acetoxymethyl-2-azabicyclo[2.2.1]hept-5-en-3-one 
• 102579-71-5 (-)-(1S, 4R)-4-amino-2-cyclopentene-1-carboxylic acid 
• 49805-30-3 racemic 2-azabicyclo[2.2.1]hept-5-en-3-one 
• 49805-30-3 2-azabicyclo[2.2.1.]hept-5-en-3-one 
• 102579-71-5 cis-4-amino-cyclopent-2-ene-1-carboxylic acid 
• 419563-22-7 (1S,4R)-4-aminocyclopent-2-ene-1-carboxylic acid methyl ester tartrate 
• 157810-21-4 (1R,4S)-N-hydroxymethyl-2-azabicyclo<2.2.1>hept-5-en-3-one 
• 157732-10-0 2-hydroxymethyl-2-azabicyclo<2.2.1>hept-5-en-3-one 

Downstream Products

• 851916-44-4 (1R,4S)-methyl 4-(2,5-dimethyl-1H-pyrrol-1-yl)cyclopent-2-enecarboxylate 
• 68715-64-0 (1β,3β,4β)-4-amino-3-hydroxycyclopentanemethanol 
• 23722-97-6 (1R*,2R*,4S*)-2-(6-Amino-9H-purin-9-yl)-4-(hydroxymethy)lcyclopentanol 
• 23722-96-5 (+/-)-6-Chlor-5-amino-4-(2trans-hydroxy-4cis-hydroxymethyl-cyclopentyl-ref-amino)-pyrimidin 
• 68715-64-0 (+/-)-(1α,3α,4β)-3-amino-4-hydroxycyclopentanemethanol 
• 229613-93-8 (+)-methyl (3aR,4R,6S,6aS)-4-[(tert-butoxycarbonyl)-amino]-3-(1-ethylpropyl)-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]isoxazole-6-carboxylate 
• 61865-49-4 ester methylique de l'acide (acetamido-cis-4)-cyclopentene-2-carboxylique 

Relevant articles and documents

Treatment method of by-product after enzymatic resolution of gamma-lactam

The invention provides a treatment method of a by-product after enzymatic resolution of gamma-lactam. The treatment method comprises the following steps of carrying out racemization catalytic reactionon the by-product (+)1-amino-4-formate-2-cyclopentene,

Diastereoselective Diboration of Cyclic Alkenes: Application to the Synthesis of Aristeromycin

The Pt-catalyzed diboration of cyclic alkenes is extended to unsaturated heterocycles and bicyclic compounds and can be accomplished in a diastereoselective fashion. The optimal procedures, substrate scope, and diastereoselectivity were investigated, and examples employing both homogeneous and heterogeneous catalysis were examined. Lastly, application to the construction of the nucleoside analog (±)-aristeromycin was conducted.

Substituent and solvent effects in the 1,3-dipolar cycloadditions for synthesis of anti-influenza agent peramivir and its analog

Influenza remains a health problem to humans. Peramivir is a FDA approved anti-influenza drug targeting the virus neuraminidase. The (3 + 2) cycloaddition reaction of 2-ethylbutanenitrile oxide with the cyclopentene dipolarophile derived from Vince lactam is a key step in the conventional synthesis of peramivir. Our study showed that conducting the (3 + 2) cycloaddition reactions with either aliphatic or aromatic nitrile oxide in hexane solution provided high percentage of the desired regioisomer, and the N-substituent having electron-withdrawing property is also beneficial to the regioselectivity. This study also demonstrated an alternative synthetic pathway of (?)-peramivir and the analog having a phenyl group in place of the 3-pentyl moiety.