152298-93-6Relevant academic research and scientific papers
PRACTICAL EPC SYNTHESIS OF 1,2- AND 1,3-AMINO ALCOHOLS
Gmeiner, Peter,Kaertner, Annerose,Junge, Dagmar
, p. 4325 - 4326 (1993)
An efficient synthesis of enantiomerically pure 1,2- and 1,3-amino alcohols (4,10) through the key intermediates 2 and 8a,b, obtained from L-aspartic acid, is reported.Using 4d as an example it is shown that the products can serve as percursors for unusual amino aldehydes and nonproteinogenic amino acids.
Enantiomerically pure amino alcohols and diamino alcohols from L-aspartic acid. Application to the synthesis of epi- and diepislaframine
Gmeiner,Junge,Kartner
, p. 6766 - 6776 (2007/10/02)
Starting from natural aspartic acid (6) a practical method for the synthesis of enantiomerically pure 3-amino alcohols 8 including 3,4-diamino derivatives is described. After perbenzylation of 6 and reduction of both carboxylates, position 4 of the result
