152360-64-0

Basic information

• Product Name: 1-(1,1-Dimethoxy-ethyl)-4-isobutyl-benzene
• Synonyms: 1-(1,1-Dimethoxy-ethyl)-4-isobutyl-benzene
• CAS NO: 152360-64-0
• Molecular Weight: 222.327
• Mol File: 152360-64-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(1,1-Dimethoxy-ethyl)-4-isobutyl-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1,1-Dimethoxy-ethyl)-4-isobutyl-benzene(152360-64-0)
• EPA Substance Registry System: 1-(1,1-Dimethoxy-ethyl)-4-isobutyl-benzene(152360-64-0)

Safety Data

• Hazardous Substances Data: 152360-64-0(Hazardous Substances Data)

Upstream product

• 38861-78-8 1-(4-isobutyl-phenyl)-ethanone 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 152361-06-3 (R)-2-(4-Isobutyl-phenyl)-2-methyl-benzo[1,3]dioxole-5-carboxylic acid 
• 181297-59-6 2-methyl-2-[4-(2-methylpropyl)phenyl]-1,3-benzodioxolane-5-carboxylic acid 
• 15687-27-1 ibuprofen 
• 40150-92-3 1-(4-isobutylphenyl)ethanol 

Relevant articles and documents

The development of non-steroidal dual inhibitors of both human 5α- reductase isozymes

The design, synthesis and biological properties of homochiral non- steroidal inhibitors of both isozymes of human 5α-reductase are described. The o-hydroxy aniline moiety of the initial lead (1) can be replaced by a 3- acyl indole isostere, whilst the minimum energy conformation of the benzyl ether in the potent inhibitor (3) is mimicked by the conformationally locked benzodioxolane system in the potent non-steroidal inhibitor (7). Pharmacokinetics and oral efficacy in a rat model of BPH are presented for (3) and (7).