152386-87-3

Upstream product

• 2186-92-7 p-Anisaldehyde dimethyl acetal 
• 135972-13-3 (2S,3S)-2,3-O-(4-methoxybenzylidene)-diethyl tartrate 
• 152386-83-9 [(4R,5R)-5-Hydroxymethyl-2-(4-methoxy-phenyl)-[1,3]dioxolan-4-yl]-methanol 
• 152386-84-0 (2R,3R)-2-O-(4-methoxybenzyl)-1,2,3,4-butanetetrol 
• 152386-85-1 (1R,2S)-1-((R)-2,2-diethyl-1,3-dioxolan-4-yl)-2-((4-methoxybenzyl)oxy)ethan-1-ol 

Downstream Products

• 247221-10-9 (3R)-3-[(4R)-2,2-diethyl-[1,3]dioxolan-4-yl]-3-(4-methoxybenzyloxy)propene 
• 152386-86-2 (2R,3R,4E)-1,2-O-pentylidene-3-(4-methoxybenzyl)-4-octadecen-1,2,3-triol 
• 247221-12-1 (3R)-3-[(4R)-2,2-diethyl-[1,3]dioxolan-4-yl]-3-(4-methoxybenzyloxy)propanal 
• 247221-11-0 (3R)-3-[(4R)-2,2-diethyl-[1,3]dioxolan-4-yl]-3-(4-methoxybenzyloxy)propan-1-ol 
• 247221-13-2 (4R)-4-phenylmethyl-3-[[(5R)-5-[(4R)-2,2-diethyl-[1,3]dioxolan-4-yl]]-(2R,3R)-3-hydroxy-5-(4-methoxybenzyloxy)-2-methyl-pentanoyl]-oxazolidin-2-one 

Relevant academic research and scientific papers

Synthetic method of homoallylic alcohol compound

The invention belongs to the technical field of chemical synthesis, and more specifically relates to a synthetic method of homoallylic alcohol compound (1R, 2S)-1-((R)-2, 2-diethyl-1, 3-dioxolane-4-yl)-1-((4-methoxybenzyl)oxo) penta-4-en-2-ol. The synthet

Synthesis of the FG ring fragment of pectenotoxins 1-9

The synthesis of the FG ring fragment common to pectenotoxins 1-9 is reported.The successful, convergent synthesis relied on high yielding routes to access two key intermediates; aldehyde 1 and phosphonium salt 2.A Z-selective Wittig reaction gave access

An aldol approach to a building block corresponding to the C21-C26-part of FK506

Starting from D-tartrate 2, the chiral aldehyde 10 was prepared in 8 steps. Key steps include the reductive opening of the p-methoxybenzyl acetal 4 and the elongation of the aldehyde 7 via Wittig and hydroboration reaction providing the alcohol 9. Subsequent Evans aldol reaction provided compound 12 which corresponds to the C21-C26 part of the immunosuppressive FK506. Wiley-VCH Verlag GmbH, 1999.

An enantiospecific synthesis of D-erythro-sphingosine from D-tartaric acid

An efficient enantiospecific synthesis of D-erythro-sphingosine (1) via azidosphingosine (2) is described, the absolute stereochemistry being derived from D-tartaric acid.