152392-00-2Relevant academic research and scientific papers
Synthesis of nucleoside α-hydroxy phosphonates
McEldoon, Wenkui Lan,Lee, Koo,Wiemer, David F.
, p. 5843 - 5846 (1993)
Nucleophilic addition of a dialkyl phosphite anion to 2′- or 3′-keto nucleosides results in an efficient synthesis of 2′-hydroxy-2′-phosphono- or 3′-hydroxy-3′-phosphononucleosides. The stereochemistry of one such adduct, 5′-O-trityl-3′-β-hydroxy-3′-α-(di
Synthesis of nucleoside 3′-phosphonates via 3′-keto nucleosides
McEldoon, Wenkui Lan,Wiemer, David F.
, p. 7131 - 7148 (2007/10/02)
Nucleophilic addition of diethyl phosphite anion to several 2′- or 3′-keto nucleosides results in an efficient synthesis of 2′-hydroxy-2′-phosphono- or 3′-hydroxy-3′-phosphononucleosides. The stereochemistry of one such adduct, 3′α-diethylphosphono-3′β-hy
