152482-50-3Relevant academic research and scientific papers
Synthesis and pharmacological investigation of new chiral muscarinic antagonists
Carnielli,De Amici,De Micheli,Gianferrara,Maurich,Zacchigna,Grana,Boselli
, p. 21 - 27 (2007/10/02)
The two pairs of enantiomers of isoxazolidin-3-ones 3 and 4 were synthesized by means of Lipase PS-catalyzed hydrolyses of suitable racemic butyrates. The same butyrates were also employed as key intermediates in the preparation of racemic 3 and 4. The an
Nitrile oxides in medicinal chemistry. 5. Lipase PS-catalyzed resolution of a set of heterocyclic derivatives
Carrea,De Amici,De Micheli,Liverani,Carnielli,Riva
, p. 1063 - 1072 (2007/10/02)
Lipase from Pseudomonas cepacia (lipase PS) catalyzed the hydrolysis of a series of butyrates of racemic primary alcohols carrying a Δ2-isoxazoline or an isoxazolidin-3-one nucleus. Within this set of compounds, the enantiopreference of the cat
