152499-89-3Relevant academic research and scientific papers
Synthesis and Absolute Stereochemistry of (-)-Protolichesterinic Acid, Antitumor Antibiotic Lactone from Cetraria islandica
Murta, Maria M.,Azevedo, Mariangela B. M. de,Greene, Andrew E.
, p. 7537 - 7541 (1993)
The first synthesis of (-)-protolichesterinic acid is described.The approach, based on a facially selective 2 + 2 cycloaddition reaction of dichloroketene with an enantiopure O-alkyl enol ether, permits the assignment of the absolute stereochemistry of th
