
Journal of Organic Chemistry p. 7537 - 7541 (1993)
Update date:2022-08-04
Topics:
Murta, Maria M.
Azevedo, Mariangela B. M. de
Greene, Andrew E.
The first synthesis of (-)-protolichesterinic acid is described.The approach, based on a facially selective 2 + 2 cycloaddition reaction of dichloroketene with an enantiopure O-alkyl enol ether, permits the assignment of the absolute stereochemistry of th
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