152565-99-6

Basic information

• Product Name: N-(1-Phenylpropionyl)-4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine
• Synonyms: N-(1-Phenylpropionyl)-4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine
• CAS NO: 152565-99-6
• Molecular Formula: C20H20 Cl N O
• Molecular Weight: 325.83
• Mol File: 152565-99-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 480°Cat760mmHg
• Flash Point: 244.1°C
• Appearance: /
• Density: 1.17g/cm³
• Vapor Pressure: 2.24E-09mmHg at 25°C
• Refractive Index: 1.594
• CAS DataBase Reference: N-(1-Phenylpropionyl)-4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-Phenylpropionyl)-4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine(152565-99-6)
• EPA Substance Registry System: N-(1-Phenylpropionyl)-4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine(152565-99-6)

Safety Data

• Hazardous Substances Data: 152565-99-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C20H20ClNO/c21-19-8-6-16(7-9-19)17-10-13-22(14-11-17)15-12-20(23)18-4-2-1-3-5-18/h1-10H,11-15H2

Upstream product

• 50-00-0 formaldehyd 
• 51304-61-1 4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride 
• 98-86-2 acetophenone 

Relevant articles and documents

Synthesis of 1-Azabicyclonona-3,6-diene Derivatives by a Modified Prins Reaction

Intramolecular electrophilic cyclization reactions were performed with 1-(3-oxo-3-phenylpropyl)-1,2,5,6-tetrahydropyridine derivatives 1a-p in strong acids to give 4,6-diphenyl-substituted 1-azabicyclononadienes 2a-p.Some qualitative observations were made on substituents and reaction conditions influencing the ring closure reaction.Naphthyl-substituted starting compounds 3a, b were converted into pentacyclic compounds 4a, b which represent a new ring system, suggesting the occurrence of a carbenium ion intermediate in the ring closure reaction.Some of the compounds 2a-p show remarkable antifungal and antibacterial effects. - Key Words: Prins reactions / Carbenium ions / 1-Azabicyclononadienes / Isogranatanines / Antifungal agents / Antibacterial agents