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15258-55-6

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15258-55-6 Usage

Description

2,3,4-Trimethoxybenzaldehyde oxime is a chemical compound that is commonly used in organic synthesis and pharmaceutical research. It is a derivative of the aldehyde group, containing three methoxy groups attached to the benzene ring. 2,3,4-TRIMETHOXYBENZALDEHYDE OXIME is known for its ability to form stable complexes with metal ions, making it useful in the chelation and extraction of metal compounds. It also has potential applications as a chelating agent in analytical chemistry and as a building block in the synthesis of various organic compounds. Additionally, 2,3,4-Trimethoxybenzaldehyde oxime is being studied for its potential medicinal properties, including antioxidant and antimicrobial effects.

Uses

Used in Organic Synthesis:
2,3,4-Trimethoxybenzaldehyde oxime is used as a building block for the synthesis of various organic compounds, contributing to the development of new chemical entities and materials.
Used in Pharmaceutical Research:
2,3,4-Trimethoxybenzaldehyde oxime is used as a chelating agent in pharmaceutical research, facilitating the chelation and extraction of metal compounds, which can be crucial for the development of new drugs and therapies.
Used in Analytical Chemistry:
2,3,4-Trimethoxybenzaldehyde oxime is used as a chelating agent in analytical chemistry, aiding in the separation and analysis of metal ions in various samples.
Used in Antioxidant Applications:
2,3,4-Trimethoxybenzaldehyde oxime is being studied for its potential antioxidant properties, which could be beneficial in the development of treatments for various diseases and conditions associated with oxidative stress.
Used in Antimicrobial Applications:
2,3,4-Trimethoxybenzaldehyde oxime is being investigated for its potential antimicrobial effects, which could lead to the development of new antimicrobial agents and treatments for infectious diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 15258-55-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,2,5 and 8 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 15258-55:
(7*1)+(6*5)+(5*2)+(4*5)+(3*8)+(2*5)+(1*5)=106
106 % 10 = 6
So 15258-55-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H13NO4/c1-13-8-5-4-7(6-11-12)9(14-2)10(8)15-3/h4-6,12H,1-3H3

15258-55-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[(2,3,4-trimethoxyphenyl)methylidene]hydroxylamine

1.2 Other means of identification

Product number -
Other names 2,3,4-Trimethoxybenzaldehyde oxime

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15258-55-6 SDS

15258-55-6Downstream Products

15258-55-6Relevant articles and documents

HCl-mediated cascade cyclocondensation of oxygenated arylacetic acids with arylaldehydes: one-pot synthesis of 1-arylisoquinolines

Hsueh, Nai-Chen,Chen, Shin-Mei,Lin, Chun-Yi,Chang, Meng-Yang

, p. 1047 - 1059 (2021/02/16)

In this paper, a concise, open-vessel synthesis of 1-arylisoquinolines is describedviaHCl-mediated intermolecular cyclocondensation of oxygenated arylacetic acids with arylaldehydes in the presence of NH2OH and alcoholic solvents under mild and one-pot reaction conditions. A plausible mechanism is proposed and discussed herein. In the overall reaction process, only water was generated as the byproduct. Various environmentally friendly reaction conditions are investigated for convenient transformationviathe (4C + 1C + 1N) annulation. This protocol provides a highly effective ring closureviathe formations of one carbon-carbon (C-C) bond, two carbon-nitrogen (C-N) bonds and one carbon-oxygen (C-O) bond.

Synthesis and SAR study of simple aryl oximes and nitrofuranyl derivatives with potent activity against Mycobacterium tuberculosis

Calixto, Stephane Lima,Carvalho, Guilherme da Silva Louren?o,Coimbra, Elaine Soares,Granato, Juliana da Trindade,Louren?o, Maria Cristina da Silva,Wardell, James,da Costa, Cristiane Fran?a,de Souza, Marcus Vinicius Nora

, p. 12 - 20 (2020/02/06)

Background: Oximes and nitrofuranyl derivatives are particularly important compounds in medicinal chemistry. Thus, many researchers have been reported to possess antibacterial, antiparasitic, insecticidal and fungicidal activities. Methods: In this work, we report the synthesis and the biological activity against Mycobacterium tuberculosis H37RV of a series of fifty aryl oximes, ArCH=N-OH, I, and eight nitrofuranyl compounds, 2-nitrofuranyl-X, II. Results: Among the oximes, I: Ar = 2-OH-4-OH, 42, and I: Ar = 5-nitrofuranyl, 46, possessed the best activity at 3.74 and 32.0 μM, respectively. Also, 46, the nitrofuran compounds, II; X = MeO, 55, and II: X = NHCH2Ph, 58, (14.6 and 12.6 μM, respectively), exhibited excellent biological activities and were non-cytotoxic. Conclusion: The compound 55 showed a selectivity index of 9.85. Further antibacterial tests were performed with compound 55 which was inactive against Enterococcus faecalis, Klebisiella pneumonae, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella typhymurium and Shigel-la flexneri. This study adds important information to the rational design of new lead anti-TB drugs. Structure-activity Relationship (SAR) is reported.

Continuous Platform to Generate Nitroalkanes On-Demand (in Situ) Using Peracetic Acid-Mediated Oxidation in a PFA Pipes-in-Series Reactor

Tsukanov, Sergey V.,Johnson, Martin D.,May, Scott A.,Kolis, Stanley P.,Yates, Matthew H.,Johnston, Jeffrey N.

supporting information, p. 971 - 977 (2018/08/28)

The synthetic utility of the aza-Henry reaction can be diminished on scale by potential hazards associated with the use of peracid to prepare nitroalkane substrates and the nitroalkanes themselves. In response, a continuous and scalable chemistry platform to prepare aliphatic nitroalkanes on-demand using the oxidation of oximes with peracetic acid and direct reaction of the nitroalkane intermediate in an aza-Henry reaction is reported. A uniquely designed pipes-in-series plug-flow tube reactor addresses a range of process challenges, including stability and safe handling of peroxides and nitroalkanes. The subsequent continuous extraction generates a solution of purified nitroalkane, which can be directly used in the following enantioselective aza-Henry chemistry to furnish valuable chiral diamine precursors with high selectivity, thus completely avoiding isolation of the potentially unsafe low-molecular-weight nitroalkane intermediate. A continuous campaign (16 h) established that these conditions were effective in processing 100 g of the oxime and furnishing 1.4 L of nitroalkane solution.

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