1526-16-5 Usage
Uses
Used in Pharmaceutical Industry:
5-Fluoro-6-hydroxynicotinic acid is used as a key intermediate in the synthesis of Favipiravir for the treatment of advanced Ebola virus infection in small animal models. Its incorporation into the drug's structure allows for the inhibition of the viral RNA-dependent RNA polymerase, thereby disrupting the replication process of the Ebola virus and offering a potential therapeutic solution for this severe and often fatal disease.
Check Digit Verification of cas no
The CAS Registry Mumber 1526-16-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,2 and 6 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1526-16:
(6*1)+(5*5)+(4*2)+(3*6)+(2*1)+(1*6)=65
65 % 10 = 5
So 1526-16-5 is a valid CAS Registry Number.
1526-16-5Relevant academic research and scientific papers
Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor
Ando, Makoto,Sato, Nagaaki,Nagase, Tsuyoshi,Nagai, Keita,Ishikawa, Shiho,Takahashi, Hirobumi,Ohtake, Norikazu,Ito, Junko,Hirayama, Mioko,Mitobe, Yuko,Iwaasa, Hisashi,Gomori, Akira,Matsushita, Hiroko,Tadano, Kiyoshi,Fujino, Naoko,Tanaka, Sachiko,Ohe, Tomoyuki,Ishihara, Akane,Kanatani, Akio,Fukami, Takehiro
experimental part, p. 6106 - 6122 (2009/12/24)
A series of 2-pyridone-containing imidazoline derivatives was synthesized and evaluated as neuropeptide Y Y5 receptor antagonists. Optimization of the 2-pyridone structure on the 2-position of the imidazoline ring led to identification of 1-(difluoromethy
