15263-52-2 Usage
Uses
Cartap hydrochloride is used to control sucking and chewing
insects (particularly Lepidoptera and Coleoptera), at almost all stages of
development, on many crops including rice, potatoes, cabbage and other
vegetables. It is also used on soya, peanuts, sunflower, maize, sugar beet,
wheat, pearl barley, pome, stone and citrus fruit, vines, tea, chestnuts,
ginger, cotton and sugar cane.
Agricultural Uses
Insecticide: Cartap hydrochloride is used to control chewing and sucking insects on many crops, including rice, potatoes, cabbage and other vegetables, soy beans, peanuts, sunflowers, maize, sugar beet, wheat, pearl barley, pome fruit, stone fruit, citrus fruit, vines, chestnuts, ginger, tea, cotton, and sugar cane. Not currently registered in the U.S. or registered for use in EU countries. There are approximately 15 global suppliers.
Trade name
CADAN?; CALDAN?; KRITAP?; NTD 2?; PADAN?; PATAP?; SANVEX?; THIOBEL?; TI1258?; VEGETOX?
Safety Profile
Poison by ingestion andintravenous routes. An experimental teratogen. Aninsecticide. When heated to decomposition it emits verytoxic fumes of NOx, SOx, and HCl.
Metabolic pathway
Nereistoxin, 4-N,N-dimethylamino-1,2-dithiolane, is
produced from cartap hydrochloride as a main product
through photoreaction under UV irradiation in aqueous
and methanolic solutions, and on glass and silica gel
surfaces. Cartap hydrochloride is also oxidized with
N-bromosuccinimide (NBS) to give nereistoxin.
Degradation
Cartap hydrochloride was hydrolysed to dihydronereistoxin (2) when
automatically titrated with sodium hydroxide solution and subsequently
oxidised to nereistoxin (3) (see Scheme 1). The hydrolysis was a base
catalysed pseudo-first-order reaction with a half-life of 10 minutes at pH 7
and 25 °C. Nereistoxin was so stable that no degradation was observed
after 24 hours at 100 °C and with pH in the range 1-4. The DT50 s of nereistoxin at 100 °C and at the higher pH values of 7/10 and 12.3 were 26,20
and 7.9 hours, respectively. It was predicted that nereistoxin (3) would
be hydrolysed by alkali to the 3-mercaptopropanesulfenic acid (4) which
would be oxidised to the sulfinic acid (5) and thence to the sulfonic acid
(6) (Asahi and Yoshida, 1977).
An aqueous solution of unlabelled cartap hydrochloride was exposed
to sunlight for a period of 5 days. Analysis was by IR, UV and MS
methods. Three products were isolated after irradiation and the major
of these was identified as a polymer of nereistoxin (7) and represented 80% of applied dose. The polymer (7) was not toxic to fish (Oryzias latips).
Cartap was hydrolysed to nereistoxin (3) via dihydronereistoxin (2).
Nereistoxin (3) was converted into the polymer (7) probably after photolytic
formation of a nereistoxin diradical as shown in Scheme 1 (Obayashi
and Asaka, 1983).
Check Digit Verification of cas no
The CAS Registry Mumber 15263-52-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,2,6 and 3 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 15263-52:
(7*1)+(6*5)+(5*2)+(4*6)+(3*3)+(2*5)+(1*2)=92
92 % 10 = 2
So 15263-52-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H15N3O2S2.ClH/c1-10(2)5(3-13-6(8)11)4-14-7(9)12;/h5H,3-4H2,1-2H3,(H2,8,11)(H2,9,12);1H
15263-52-2Relevant articles and documents
Synthesis method of cartap
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Paragraph 0042; 0043; 0044; 0045; 0046; 0047; 0048, (2017/07/21)
The invention provides a synthesis method of cartap, and relates to a synthesis method of 1,3-bis(carbamyl sulfonium)-2-(N,N-dimethylamino) propane hydrochloride. An original medicine of cartap is prepared from carbon oxysulfide, ammonia and 1-(N,N-dimethylamino)-2,3-propylene dichloride (chloride for short) through a one-pot method in an alkaline solution. By the adoption of the one-pot method for reaction step by step to prepare the cartap, the synthesis method has the advantages of low equipment investment, low energy consumption, easiness and convenience for operation and substantial improvement of the conversion rate. According to the synthesis method, the use of organic raw materials such as sodium thiosulfate (sodium thiosulfate) and sodium cyanide is avoided, so that generation of a large amount of sewage containing sodium sulfite and sodium cyanide is avoided. The synthesis method substantially increases the selectivity and the conversion rate in a reaction process, thus improving the production efficiency and greatly reducing the production cost.
Pyrazole oxime derivatives and compositions
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, (2008/06/13)
A pyrazole oxime derivative represented by the general formula (I) which is useful as an insecticide and fungicide, STR1 wherein the structural elements are defined in the specification, and the method of controlling said pests. The compounds represented by the general formula (I) can be synthesized by the methods disclosed in the specification.
