15263-53-3 Usage
Chemical Properties
solid
Uses
Cartap is obtained by hydrolyzing 1,1-dithiocyanato-
2-dimethylaminopropane with hydrochloric acid. Cartap
is the pro-insecticide of the natural toxin nereistoxin. It
is used for the control of chewing and sucking insects, at almost all stages of development, on many crops. Its
structure is based on that of the naturally occurring neurotoxin,
nereistoxin.
Metabolism
Cartap is hydrolyzed in base to the dihydronereistoxin,
which is oxidized to the insecticide, nereistoxin
(32). The conversion occurs within plants, and the
monoxide (33)was identified as aminor metabolite. In rats,
cartap was rapidly excreted in urine. It was hydrolyzed,
converted to the sulfoxide, and N-demethylated (9).
Toxicity evaluation
Nereistoxin does not inhibit cholinesterase. Instead, it
acts as an antagonist at the nicotinic acetylcholine receptor
and blocks neural transmission (10).
Check Digit Verification of cas no
The CAS Registry Mumber 15263-53-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,2,6 and 3 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 15263-53:
(7*1)+(6*5)+(5*2)+(4*6)+(3*3)+(2*5)+(1*3)=93
93 % 10 = 3
So 15263-53-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H15N3O2S2/c1-10(2)5(3-13-6(8)11)4-14-7(9)12/h5H,3-4H2,1-2H3,(H2,8,11)(H2,9,12)
15263-53-3Relevant articles and documents
Synthesis method of cartap
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Paragraph 0029-0041, (2017/07/21)
The invention provides a synthesis method of cartap, and relates to a synthesis method of 1,3-bis(carbamyl sulfonium)-2-(N,N-dimethylamino) propane hydrochloride. An original medicine of cartap is prepared from carbon oxysulfide, ammonia and 1-(N,N-dimethylamino)-2,3-propylene dichloride (chloride for short) through a one-pot method in an alkaline solution. By the adoption of the one-pot method for reaction step by step to prepare the cartap, the synthesis method has the advantages of low equipment investment, low energy consumption, easiness and convenience for operation and substantial improvement of the conversion rate. According to the synthesis method, the use of organic raw materials such as sodium thiosulfate (sodium thiosulfate) and sodium cyanide is avoided, so that generation of a large amount of sewage containing sodium sulfite and sodium cyanide is avoided. The synthesis method substantially increases the selectivity and the conversion rate in a reaction process, thus improving the production efficiency and greatly reducing the production cost.