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Evocarpine, a quinazolinocarboline alkaloid, is a chemical compound derived from the Evodia rutaecarpa plant, commonly known as Wu Chu Yu in traditional Chinese medicine. It possesses a range of pharmacological properties, including anti-inflammatory, anti-cancer, and neuroprotective effects. evocarpine's ability to modulate neurotransmitter activity, such as dopamine and serotonin, also suggests potential applications in treating psychiatric disorders. Evocarpine's diverse pharmacological profile makes it a promising candidate for various therapeutic uses.

15266-38-3

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15266-38-3 Usage

Uses

Used in Anti-inflammatory Applications:
Evocarpine is used as an anti-inflammatory agent for its potential to reduce inflammation, which can be beneficial in treating various inflammatory conditions.
Used in Anticancer Applications:
Evocarpine is used as an anticancer agent for its ability to inhibit tumor growth, making it a potential candidate for cancer treatment and prevention.
Used in Neuroprotective Applications:
Evocarpine is used as a neuroprotective agent for its potential to protect against neurodegenerative diseases such as Alzheimer's, offering a natural approach to managing these conditions.
Used in Psychiatric Disorder Treatment:
Evocarpine is used as a therapeutic agent in the treatment of psychiatric disorders due to its ability to modulate neurotransmitter activity, which can help alleviate symptoms associated with these conditions.
Used in Pharmaceutical Industry:
Evocarpine is used as a key ingredient in the development of pharmaceutical products for its diverse pharmacological properties, including anti-inflammatory, anti-cancer, neuroprotective, and potential psychiatric disorder treatment applications.
Used in Traditional Chinese Medicine:
Evocarpine is used as a component in traditional Chinese medicine formulations, leveraging its various pharmacological benefits for the treatment of different ailments and conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 15266-38-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,2,6 and 6 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 15266-38:
(7*1)+(6*5)+(5*2)+(4*6)+(3*6)+(2*3)+(1*8)=103
103 % 10 = 3
So 15266-38-3 is a valid CAS Registry Number.
InChI:InChI=1/C23H33NO/c1-3-4-5-6-7-8-9-10-11-12-13-15-20-16-14-17-21-22(25)18-19-24(2)23(20)21/h12-14,16-19H,3-11,15H2,1-2H3/b13-12+

15266-38-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (Z)-1-Methyl-2-(tridec-8-en-1-yl)quinolin-4(1H)-one

1.2 Other means of identification

Product number -
Other names evocarpine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15266-38-3 SDS

15266-38-3Downstream Products

15266-38-3Related news

The vasorelaxant effect of evocarpine (cas 15266-38-3) in isolated aortic strips: mode of action08/03/2019

The effect of evocarpine (EVO), a quinolone alkaloid isolated from Evodiae fructus, on Ca2+-blocking activity has been examined. In the isolated rat thoracic aorta evocarpine significantly inhibited the contraction induced by 60 mM K+ with an IC50 of 9.8 μM, and that induced by external Ca2+ in...detailed

15266-38-3Relevant academic research and scientific papers

The Chemistry of 2H-3,1-Benzoxazine-2,4(1H)-dione (Isatoic Anhydride). 17. Synthesis of 2-Alkyl-4-quinolone Alkaloids via a One-step Reaction of N-Methylisatoic Anhydride with Methyl Ketone Enolates

Coppola, Gary M.

, p. 491 - 494 (2007/10/02)

Lithium enolates derived from aliphatic methyl ketones react with N-methylisatoic anhydride (5) at -78 deg C to give 2-alkyl-4-quinolone alkaloids 7 in a single step.The method was used to synthesize both double bond isomers of 1-methyl-2-(8-tridecenyl)-4(1H)-quinolinone (8) thereby showing that the alkaloid evocarpine possesses the Z-olefin stereochemistry 8a.Reduction of 8a provided the alkaloid dihydroevocarpine (16).Compound 16 was also directly prepared from the reaction of 5 with the lithium enolate of 2-pentadecanone.

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