1527-98-6

Usage

Uses

Used in Chemical Analysis:
N-BUTYRALDEHYDE 2,4-DINITROPHENYLHYDRAZONE is used as a chemical marker for the detection and analysis of aldehydes in various environments, including cigarette smoke. Its presence in cigarette smoke makes it a relevant compound for studying the chemical composition and potential health effects of smoking.
Used in Environmental Monitoring:
In the environmental monitoring industry, N-BUTYRALDEHYDE 2,4-DINITROPHENYLHYDRAZONE is used as an indicator for assessing the levels of aldehydes in the air, particularly in areas where cigarette smoke is a concern. This helps in understanding the potential health risks associated with exposure to secondhand smoke and in developing strategies to mitigate these risks.
Used in Tobacco Industry Research:
Within the tobacco industry, N-BUTYRALDEHYDE 2,4-DINITROPHENYLHYDRAZONE is used as a research compound to study the effects of different cigarette formulations on the production of aldehydes and other harmful chemicals. This information can be used to develop products with reduced harmful emissions, potentially benefiting both smokers and those exposed to secondhand smoke.
Used in Public Health Research:
In public health research, N-BUTYRALDEHYDE 2,4-DINITROPHENYLHYDRAZONE is used as a reference compound to investigate the relationship between exposure to cigarette smoke and various health outcomes. This can help in developing educational campaigns, smoking cessation programs, and public policies aimed at reducing the prevalence of smoking and its associated health risks.

InChI:InChI=1/C10H12N4O4/c1-2-3-6-11-12-9-5-4-8(13(15)16)7-10(9)14(17)18/h4-7,12H,2-3H2,1H3

Upstream product

• 2319-38-2 triphenylsilyl hydroperoxide 
• 119-26-6 (2,4-dinitro-phenyl)-hydrazine 
• 42196-80-5 2-(n-propyl)-1,3-dithiane 
• 64-17-5 ethanol 
• 7664-93-9 sulfuric acid 
• 123-72-8 butyraldehyde 
• 32375-05-6 N-[1-((1-cyano-2-methylpropyl)hydroxyamino)butyl]formamide 
• 91015-19-9 Butyraldehyd-(ethyl-butyl-hydrazon) 

Downstream Products

• 115591-32-7 1-(2,4-Dinitro-phenyl)-5-methyl-3-propyl-1H-[1,2,4]triazole 
• 79348-58-6 N-(2,4-dinitrophenyl)-C-n-propylhydrazonyl chloride 
• 74305-96-7 butyryl bromide 2,4-dinitrophenylhydrazone 

Relevant academic research and scientific papers

Oxygen-to-Oxygen Silyl Migration of α-Siloxy Sulfoxides and Oxidation-Triggered Allicin Formation

Oxidation of α-siloxy thioethers leads to the formation of the corresponding sulfoxides as unstable intermediates, which undergo an intramolecular oxygen-to-oxygen silyl migration to break the C-S linkage. This process produces silyl protected sulfenic acids and subsequently thiosulfinates. It was used to develop oxidation-triggered allicin donors.

Effect of CHAPS and CPC micelles on Ir(III) catalyzed Ce(IV) oxidation of aliphatic alcohols at room temperature and pressure

Kinetics of cerium(IV) oxidation of aliphatic alcohols: ethanol, propanol, propan-2-ol, 1-butanol and 2-butanol were studied at 30 °C in the presence and absence of surfactants in acidic medium. The reaction was studied under pseudo-first-order conditions

A novel synthetic method for the preparation of aliphatic aldehydes from the corresponding carboxylic acids

A novel synthetic method for the preparation of aliphatic aldehydes from the corresponding carboxylic acids via 1,3-dimethylbenzimidazolium salts is provided. 1,3-Dimethylbenzimidazolium salts were rapidly reduced with sodium/ethanol and then hydrolyzed with hydrochloric acid to obtain aliphatic aldehydes, in which the 1,3-dimethylbenzimidazolium salts can be readily achieved from the corresponding carboxylic acids. The mechanism for the reductive reaction of 1,3-dimethylbenzimidazolium salts with sodium/ethanol was discussed.

Analysis of carbonyl compounds in sea buckthorn for the evaluation of triglyceride oxidation, by enzymatic hydrolysis and derivatisation methodology

Carbonyl compounds formed in sea buckthorn berry (Hippophae rhamnoides) and oil samples as a result of lipid oxidation were determined by enzymatic hydrolysis followed by derivatisation with 2,4-dinitrophenylhydrazine and analysed by LC-UV and electrospra

Kinetics and mechanism of the oxidation of aliphatic primary alcohols by imidazolium fluorochromate

The oxidation of nine aliphatic primary alcohols by imidazolium fluorochromate (IFC) in dimethylsulphoxide leads to the formation of corresponding aldehydes. The reaction is first order with respect to IFC. A Michaelis-Menten type kinetics is observed with respect to alcohols. The reaction is promoted by hydrogen ions; the hydrogen-ion dependence has the form : kobs = a + b [H+]. The oxidation of [1,1- 2H2]ethanol (MeCD2OH) exhibits a substantial primary kinetic isotope effect (kH/kD = 5.87 at 298 K). The reaction has been studied in nineteen different organic solvents. The solvent effect was analysed using Taft's and Swain's multiparametric equations. The rate of oxidation is susceptible to both polar and steric effects of the substituents. A suitable mechanism has been proposed.

Oxidation of aliphatic primary alcohols by morpholinium chlorochromate: A kinetic and mechanistic approach

The oxidation of nine aliphatic primary alcohols by morpholinium chlorochromate (MCC) in dimethylsulfoxide leads to the transformation of alcohols to the corresponding aldehydes. The reaction is first order with respect to both MCC and the alcohol both. The reaction is catalysed by hydrogen ions. The hydrogen-ion dependence has the form: kobs = a + A[H +]. The oxidation of [1,1-2H2]ethanol (MeCD2OH) exhibits a substantial primary kinetic isotope effect. The reaction has been studied in nineteen different organic solvents. The solvent effect was analysed using Taft's and Swain's multiparametric equations. The rate of oxidation is susceptible to both polar and steric effects of the substituents. A suitable mechanism has been proposed.

A facile mild deprotection protocol for 1,3-dithianes and 1,3-dithiolanes with 30% hydrogen peroxide and iodine catalyst in aqueous micellar system

A simple clean expeditious protocol for the deprotection of 1,3-dithianes and 1,3-dithiolanes has been developed using 30% aqueous hydrogen peroxide activated by iodine catalyst (5 mol%) in water in the presence of sodium dodecyl sulfate (SDS) under essentially neutral conditions. The method showed tolerance for a number of phenol protecting groups such as allyl, benzyl, TBDMS, TBDPS ethers, phenolic acetates, and benzoates as well as amino-protecting BOC, Cbz carbamates without any detectable overoxidation. Georg Thieme Verlag Stuttgart.

Reactions of titanium alcoholates Ti(OR)4 (R = n-Bu, t-Bu) with tertiary organic and organometallic hydroperoxides

tert-Butyl and cumyl hydroperoxides in the reactions with Ti(OR) 4 are reduced to alcohols with the evolution of oxygen via formation of titanium-containing peroxides and trioxides. The pathways of the reactions of Ti(OR)4 with triphenylelement hydroperoxides R3EOOH (E = C, Si, Ge) depend on element E and on the structure of R; the reactions involve the rearrangement of the peroxides, and with (n-BuO)4Ti the alkoxy group is oxidized either with preservation or with breakdown of the hydrocarbon skeleton. Pleiades Publishing, Inc., 2006.

Quantitative RP-HPLC determination of some aldehydes and hydroxyaldehydes as their 2,4-dinitrophenylhydrazone derivatives

A high-performance liquid chromatographic (HPLC) method is described for the quantitative determination of some aliphatic aldehydes and β- hydroxyaldehydes as their 2,4-dinitrophenylhydrazone derivatives. A method is described for the preparation of deriv

KINETICS OF THE FORMATION OF 2,4-DINITROPHENYLHYDRAZONES IN HYDROCARBONS

The kinetics of the formation of 2,4-dinitrophenylhydrazones in a hydrocarbon medium were studied.By an integral method it was found that the reaction of carbonyl compounds with 2,4-dinitrophenylhydrazine is reversible, and the forward and reverse reactio