152826-43-2Relevant academic research and scientific papers
One-pot multi-component synthesis and solid state structures of functionally rich polyether macrocycles
Vishe, Mahesh,Hrdina, Radim,Guenee, Laure,Besnard, Celine,Lacour, Jerome
, p. 3161 - 3169 (2013)
Densely functionalized polyether macrocycles can be prepared in one pot in yields up to 60% by the rhodium(II)-catalyzed decomposition of methyl diazoacetoacetate in the presence of a variety of substituted or unsaturated 5- and 6-membered ring cyclic ethers. A comprehensive analysis of the solid state conformations of the macrocyclic geometries is detailed as well as novel mechanistic insights about the multi-component condensation reaction. Copyright
Cyproheptadine analogues: Synthesis, antiserotoninergic activity, and structure-activity relationships
Loza,Sanz,Cadavid,Honrubia,Orallo,Fontenla,Calleja,Dot,Manaut,Cid,Dominguez,Seijas,Villaverde
, p. 1090 - 1093 (2007/10/02)
A series of cyproheptadine related compounds was synthesized and tested pharmacologically. In comparison with cyproheptadine, these compounds do not have a central ring and some contain groups other than N-methyl. Synthesis was carried out with low-valent
