152878-34-7Relevant articles and documents
Fluoro-artemisinins: When a gem-difluoroethylene replaces a carbonyl group
Magueur, Guillaume,Crousse, Benoit,Ourévitch, Michèle,Bonnet-Delpon, Danièle,Bégué, Jean-Pierre
, p. 637 - 642 (2006)
Exo gem-difluoromethylene-artemisinins (8) has been designed to mimic artemisinin. The classical Wittig olefination reaction applied to artemisinin failed. An alternative reaction involving the generation of an α-CF3 carbanion, from the corresp