152886-16-3

Usage

Uses

Used in Sports Doping Control Analysis:
6β-Hydroxyandrosterone (available to WADA laboratories only) is used as a biomarker for the detection of doping in sports. It is employed in the analysis of athletes' samples to identify the use of prohibited anabolic androgenic steroids, ensuring fair competition and adherence to anti-doping regulations.

Upstream product

• 14456-20-3 3β-acetoxy-5-androsten-17-one-17-ethyleneketal 
• 481-29-8 Epiandrosterone 
• 1048034-76-9 17,17-ethylenedioxy-5α-androstan-3β,6α-diol 
• 899-39-8 17β-hydroxy-5α-androstane-3,6-dione 
• 2243-05-2 5α-androst-3,6,17-trione 
• 570-78-5 3α,6α-dihydroxy-5β-pregnan-20-one 
• 7766-16-7 5α-stigmastanediyl-(3β.6β)-diacetate 
• 3514-29-2 5α-cholestan-3β,6β-diol diacetate 
• 96612-04-3 5β-cholestanediyl-(3β.6β)-diacetate 
• 53-43-0 dehydroepiandrosterone 
• 64-19-7 acetic acid 
• 7664-93-9 sulfuric acid 
• 71-43-2 benzene 
• 94999-96-9 17β-Acetoxy-5β-androstandiol-(3α,6α)-dinitrat 

Downstream Products

• 49643-95-0 6α-hydroxyandrostane-3,17-dione 
• 7801-26-5 6β-hydroxyandrostane-3,17-dione 

Relevant academic research and scientific papers

ISTAROXIME-CONTAINING INTRAVENOUS FORMULATION FOR THE TREATMENT OF ACUTE HEART FAILURE (AHF)

Compositions for intravenous infusion of istaroxime, or a metabolite of istaroxime, in human patients suffering from heart failure are disclosed. Likewise, methods for extended infusion of istaroxime or its metabolites in individuals with heart failure are disclosed. In particular, some methods disclosed herein include the infusion of istaroxime, or a metabolite thereof, for a period of time that is greater than six hours in order to improve cardiac relaxation without triggering arrhythmogenic events in an individual suffering from heart failure. Other methods include administration of istaroxime until certain plasma concentration thresholds of istaroxime metabolites are achieved. Also disclosed are istaroxime metabolites with selective SERCA2a activation.

Stereoselective synthesis of Certonardolsterol D3

The first stereoselective synthesis of Certonardolsterol D3 was described. Ene reaction and improved allylic oxidation were employed as key steps for efficient construction of the desired 3β,6α,15β-triol steroidal framework. The chiral side cha

Steroid transformations with Exophiala jeanselmei var. lecanii-corni and Ceratocystis paradoxa

The fungi Exophiala jeanselmei var. lecanii-corni [IMI (International Mycological Institute) 312989, UAMH (University of Alberta Microfungus Collection and Herbarium) 8783] and Ceratocystis paradoxa (IMI 374529, UAMH 8784) have been examined for their potential in steroid biotransformation. The study has determined that E. jeanselmei var. lecanii-corni effected overall anti-Markovnikov hydration on dehydroisoandrosterone, and side-chain degradation on a variety of pregnanes. Both ascomycetes were found to carry out redox reactions of alcohols and ketones as well as 1,4 reduction of α,β-unsaturated carbonyl systems.

Antenna-initiated photochemistry in polyfunctional steroids. photoepimerization of 3α-(dimethylphenylsiloxy)-5α-androstane-6,17-dione and its 3β isomer by through-bond exchange energy transfer

We have previously reported that photolysis of 3α-(dimethylphenylsiloxy-5α-androstane-11,17-dione, in the presence of triethylamine (TEA) and with 266-nm light so as to selectively excite the dimethylphenylsiloxy (DPS) "antenna", primarily gives rise to t