15298-00-7

Upstream product

• 623-11-0 1-methyl-4-nitrosobenzene 
• 41019-50-5 3'-bromo-β-lapachone 
• 119626-45-8 3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-naphtho[2,3-b]pyran-5,10-dione 
• 74693-34-8 4'-bromo-iso-β-lapachone 
• 79060-56-3 4-Bromo-iso-α-lapachone 
• 79060-57-4 3-Bromo-α-lapachone 
• 341991-52-4 2-hydroxy-3-(2,3-dibromo-3-methylbutyl)-1,4-naphthoquinone 

Downstream Products

• 13019-42-6 2-isopropylnaphtho[1,2-b]furan-4,5-dione 
• 15297-98-0 3-Hydroxy-2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene-5,6-dione 
• 13019-43-7 2-isopropylnaphtho[2,3-b]furan-4,9-dione 

Relevant academic research and scientific papers

Reaction of Lapachol with Lead Tetraacetate and N-Bromosuccinimide

Reaction of lapachol (II) with N-bromosuccinimide and lead tetraacetate yields 3-bromo-α-lapachone (III) and 4-bromo-iso-α-lapachone (V), characterised on the basis of spectral and chemical studies.

Bromination with N-Bromosuccinimide : Part III - Formation of 3'-Bromo-β-lapachone, Dehydro-iso-β-lapachone and 4'-Bromo-iso-β-lapachone from Lapachol

Lapachol (I), on bromination with N-bromosuccinimide, affords three ortho-naphthoquinone derivatives which have been characterized to be 3'-bromo-β-lapachone (IV), dehydro-iso-β-lapachone (V) and 4'-bromo-iso-β-lapachone (X) on the basis of spectral and chemical studies.