153034-91-4 Usage
Description
2-Chloro-3,4-diiodopyridine is a chemical compound with the molecular formula C5H2ClI2N. It is a highly reactive and versatile building block in organic synthesis, commonly used in the pharmaceutical and agrochemical industries.
Uses
Used in Pharmaceutical Industry:
2-Chloro-3,4-diiodopyridine is used as a valuable precursor for the production of a wide range of organic compounds, particularly in the synthesis of biologically active molecules and complex organic materials. It plays a significant role in the creation of new pharmaceuticals and other important compounds.
Used in Agrochemical Industry:
2-Chloro-3,4-diiodopyridine is used as a versatile building block in the synthesis of agrochemicals, contributing to the development of new and effective products for agricultural applications.
Check Digit Verification of cas no
The CAS Registry Mumber 153034-91-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,0,3 and 4 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 153034-91:
(8*1)+(7*5)+(6*3)+(5*0)+(4*3)+(3*4)+(2*9)+(1*1)=104
104 % 10 = 4
So 153034-91-4 is a valid CAS Registry Number.
153034-91-4Relevant articles and documents
Iterative and regioselective cross-couplings of 2-chloro-3,4-diiodopyridine leading to 2,3,4-triheteroarylpyridines
Daykin, Laura M.,Siddle, Jamie S.,Ankers, Adrian L.,Batsanov, Andrei S.,Bryce, Martin R.
supporting information; experimental part, p. 668 - 675 (2010/09/05)
A one-pot synthesis of 2-chloro-3,4-diiodopyridine from 2-chloropyridine is described via a Directed ortho Metallation (DoM)/Halogen Dance (HD) mechanism in 26-28% yields. By performing sequential, iterative Suzuki-Miyaura cross-couplings using a variety of functionalised heteroaryl and arylboronic acids, a series of novel 2,3,4-triheteroarylpyridine scaffolds have been accessed in synthetically viable yields, including sterically hindered derivatives. 2-Chloro-4-heteroaryl-3-iodopyridines and 2-chloro-3,4-diheteroarylpyridines are also reported. The synthesis of 5-[3,4-bis(2-phenylethynyl)pyridin-2-yl]-2-fluoropyridine via a two-step Sonogashira/Suzuki-Miyaura reaction sequence from 2-chloro-3,4-diiodopyridine, phenylacetylene and 6-fluoropyridin-3-yl-3-boronic acid has been achieved in 48% overall yield.
