15307-92-3Relevant academic research and scientific papers
P(i-BuNCH2CH2)3N: An effective ligand in the palladium-catalyzed amination of aryl bromides and iodides
Urgaonkar, Sameer,Nagarajan,Verkade
, p. 452 - 459 (2003)
It is shown that the bicyclic triaminophosphine P(i-BuNCH2CH2)3N serves as an effective ligand for the palladium-catalyzed amination of a wide array of aryl bromides and iodides. Other bicyclic or acyclic triaminophosphines, even those of similar basicity and/or bulk, were inferior.
[Pd(IPr*)(acac)CI]: An easily synthesized, bulky precatalyst for C-N bond formation
Meiries, Sebastien,Chartoire, Anthony,Slawin, Alexandra M. Z.,Nolan, Steven P.
experimental part, p. 3402 - 3409 (2012/06/04)
A very straightforward synthesis of [Pd(IPr*)(acac)Cl] has been developed from commercially available Pd(acac)2 and the easily prepared IPr*·HCl (acac = acetylacetonate; IPr* = N,N′-bis(2,6-bis(diphenylmethyl)-4-methylphenyl)imidazol-2-ylidene). The reactivity of the resulting complex [Pd(IPr*)(acac)Cl] (1) as a highly active PdII precatalyst for the Buchwald-Hartwig arylamination coupling has been explored. A wide range of substrates with varying electronic and steric demands of both coupling partners has been screened successfully. The chemoselectivity of the reaction was also explored by using aryl heterodihalides.
